Sökning: "Protein S"

Visar resultat 21 - 25 av 1310 avhandlingar innehållade orden Protein S.

  1. 21. Cell cycle and differentiation in Giardia Lamblia

    Författare :David S Reiner; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Giardia lamblia is the major cause of waterborne diarrhea worldwide. Giardiasis is initiated by ingestion of cysts, which after passing through the stomach are triggered to excyst. Excystation, or awakening from dormancy, is central to successful colonization of the host. LÄS MER

  2. 22. Pharmacokinetics of 2-mercaptopropionylglycine (Tiopronin) in man

    Författare :Margaretha S. Carlsson; Per Sjöström; Linköpings universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : 2-Mercaptopropionylglycine (2-MPG, tiopronin) has been used successfully in the treatment of cystinuria despite the lack of knowledge of its pharmacokinetics. Therefore methods based on high-performance liquid chromatography and fluorometric detection were developed for quantitative analysis. LÄS MER

  3. 23. Distribution and connectivity of messenger molecules in the control of energy metabolism : focus on neuropeptides and calcium binding proteins

    Författare :Kylie S Foo; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Feeding is an essential and complex behavior which aims to provide the energy required for maintaining physiological homeostasis. The drive to feed is a powerful stimulus arising from metabolic demands, and reinforced by evolutionary pressure. LÄS MER

  4. 24. Myeloid-Derived Suppressor Cells and Other Immune Escape Mechanisms in Chronic Leukemia

    Författare :Lisa Christiansson; Angelica S I Loskog; Ulla Olsson-Strömberg; Andreas Lundqvist; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; chronic myeloid leukemia; myeloid-derived suppressor cells; sCD25; tyrosine kinase inhibitors; multiplex protein quantification; Medical Science; Medicinsk vetenskap;

    Sammanfattning : Chronic myeloid leukemia (CML) is characterized by the Philadelphia chromosome, a minute chromosome that leads to the creation of the fusion gene BCR/ABL and the transcription of the fusion protein BCR/ABL in transformed cells. The constitutively active tyrosine kinase BCR/ABL confers enhanced proliferation and survival on leukemic cells. LÄS MER

  5. 25. Roles of voltage-gated Ca2+ channel subunits in pancreatic β cells

    Författare :Abdulla S. Kazim; Diabetes - öpatofysiologi; []
    Nyckelord :diabetes; Type 2 diabetes T2D ; Ca2 ; Ca2 channels; subunits;

    Sammanfattning : Hallmarks of type 2 diabetes (T2D) include elevated blood glucose and free fatty acids (FFAs) as a result of impaired β cell insulin secretion and decreased β cell mass. The glucose-stimulated insulin secretion (GSIS) in β cells is triggered by depolarization-evoked Ca2+ entry through voltage-gated Ca2+ (CaV) channels. LÄS MER