Sökning: "Prostate growth"

Visar resultat 1 - 5 av 109 avhandlingar innehållade orden Prostate growth.

  1. 1. Androgen controlled regulatory systems in prostate cancer : potential new therapeutic targets and prognostic markers

    Författare :Peter Hammarsten; Anders Bergh; Stina Häggström Rudolfsson; Pernilla Wikström; Sten Nilsson; Umeå universitet; []
    Nyckelord :AGRICULTURAL SCIENCES; LANTBRUKSVETENSKAPER; LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES; prostate cancer; angiogenesis; human biopsy; androgen ablation; castration; prognostic marker; prognostic factor; growth control; VEGF; vascular endothelial growth factor; EGFR; epidermal growth factor receptor; pEGFR; phosphorylated EGFR; phosphorylated epidermal growth factor receptor; Pathology; Patologi;

    Sammanfattning : BACKGROUND: Prostate cancer is by far the most common cancer among Swedish men. Some patients have an aggressive lethal disease, but the majority of affected men have long expected survival. Unfortunately, the diagnostic tools available are insufficient in predicting disease aggressiveness. Novel prognostic markers are therefore urgently needed. LÄS MER

  3. 2. Prostate cancer aetiology : epidemiological studies of the IGF- and one-carbon metabolism pathways

    Författare :Mattias Johansson; Pär Stattin; Henrik Grönberg; Fredrik Wiklund; Jenny Chang-Claude; Umeå universitet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Urology and andrology; Urologi och andrologi;

    Sammanfattning : The aim of this thesis was to investigate the involvement of the insulin-like growth factor- and the one-carbon metabolism pathways in prostate cancer aetiology, studying both circulating biomarkers and genetic variation. Papers included in the thesis were conducted within the case-control study CAncer Prostate in Sweden (CAPS), and the two prospective studies European Prospective Investigation into nutrition and Cancer (EPIC), and Northern Sweden Health and Disease Cohort (NSHDC). LÄS MER

  4. 3. Prostate cancer and bone cell interactions : implications for metastatic growth and therapy

    Författare :Annika Nordstrand; Pernilla Wikström; Anders Widmark; Jonas Nilsson; Päivi Östling; Umeå universitet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; onkologi; Oncology;

    Sammanfattning : The skeleton is the most common site of prostate cancer bone metastasis, and at present, there are no curable treatments for these patients. To further understand what stimulates tumor cell growth in the bone microenvironment and to find suitable therapies, reliable model systems are needed. LÄS MER

  5. 4. Extratumoral effects of highly aggressive prostate cancer

    Författare :Kerstin Strömvall; Anders Bergh; Sofia Halin Bergström; Göran Landberg; Umeå universitet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Prostate cancer; tumor instructed normal tissue; TINT; non-malignant prostate tissue; lymph nodes; lymph node metastasis; pre-metastatic niche; tumor microenvironment; tumor macroenvironment; tumor immunoediting; Dunning rat model of prostate cancer;

    Sammanfattning : Prostate cancer (PC) is the most common cancer in Sweden. Most patients have slow growing tumors that will not cause them any harm within their lifetime, but some have aggressive tumors and will die from their disease. LÄS MER

  7. 5. Prostate cancer and inflammatory genes

    Författare :Fredrik Lindmark; Henrik Grönberg; William G Nelson; Umeå universitet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Prostate cancer; inflammation; association studies; epidemiology; MSR1; MIC-1; IL1-RN; Oncology; Onkologi; Oncology; onkologi;

    Sammanfattning : Prostate cancer remains a significant health concern for men throughout the world. Accumulating epidemiologic and molecular evidence suggests that inflammation is an important component in the aetiology of prostate cancer. LÄS MER