Sökning: "Prostate cancer"

Visar resultat 21 - 25 av 469 avhandlingar innehållade orden Prostate cancer.

  1. 21. Prostate Cancer Diagnosis : experimental and Clinical Studies With HRMAS NMR Spectroscopy

    Författare :Katarina Stenman; Katrine Åhlström-Riklund; Anders Bergh; Peter Lundberg; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Prostate cancer; PCa; HRMAS NMR; MRSI; metabolomics; Gleason score; citrate; inositol; choline; Krebs cycle; PUFA; omega-6; omega-3; Diagnostic radiology; Diagnostisk radiologi; Radiology; radiologi;

    Sammanfattning : A few abnormal cells found in a small piece of prostate tissue are most consequential for a man’s future. The prevalence of prostate cancer (PCa) is increasing globally. LÄS MER

  3. 22. How to model temporal changes in epidemiological data : Treatment trajectories in men with prostate cancer

    Författare :Eugenio Ventimiglia; Pär Stattin; Paul C. Lambert; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; prostate cancer; state transition model; life expectancy; active surveillance; watchful waiting;

    Sammanfattning : Owing to the improvements in detection, diagnostics, and treatment, many men currently diagnosed with prostate cancer (PCa) have a low risk of PCa death. For many men PCa has become a chronic disease with a small risk of progression that remains even decades after date of diag-nosis. LÄS MER

  4. 23. Molecular heterogeneity of prostate cancer bone metastasis

    Författare :Erik Bovinder Ylitalo; Pernilla Wikström; Anders Bergh; Maria Brattsand; Vessela Kristensen; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Prostate cancer; CRPC; castration-resistant; androgen receptor; splice variant; abiraterone; cabazitaxel; ABCB1; cholesterol; Mdr1; P-gp; bone metastasis; immune response; metabolism; osteoblast; osteoclast; BMP; methylation;

    Sammanfattning : Castration-resistant prostate cancer (CRPC) develops after androgen deprivation therapy of advanced PC, often with metastatic growth in bone. Patients with metastatic CRPC have very poor prognosis. Growth of CRPC, in most but not all patients, seems to involve androgen receptor (AR) activity, despite castrate levels of serum testosterone. LÄS MER

  5. 24. Magnetic Resonance Imaging as a Screening Tool for Prostate Cancer

    Författare :Kimia Kohestani; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; prostate cancer; prostate-specific antigen; magnetic resonance imaging; screening; early detection;

    Sammanfattning : The overall aim of this thesis was to explore the role of Magnetic resonance imaging (MRI) of the prostate as an adjunct to the prostate-specific antigen (PSA)-test in screening for prostate cancer (PCa), focusing on the performance of MRI in detecting clinically significant PCa within the randomised controlled GÖTEBORG Prostate Cancer Screening 2 Trial. By inviting men 50–60 years of age to different screening strategies—PSA cut-off for biopsy 3. LÄS MER

  7. 25. Identification of miRNA expression profiles for diagnosis and prognosis of prostate cancer

    Författare :Jessica Carlsson; Karin Klinga Levan; Björn Olsson; Gisela Helenius; Pernilla Wikström; Örebro universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Prostate cancer; microRNAs; prostate zones; normalization; endogenous controls; Medicin; Medicine;

    Sammanfattning : Cancer of the prostate (CaP) is the most common malignancy diagnosed in men in the Western society. During the last years, prostate specific antigen (PSA) has been used as a biomarker for CaP, although a high PSA value is not specific for CaP. Thus, there is an urgent need for new and improved diagnostic markers for CaP. LÄS MER