Sökning: "Prostate cancer"

Visar resultat 11 - 15 av 469 avhandlingar innehållade orden Prostate cancer.

1. 11. Prostate Cancer Screening - Aspects of Overdiagnosis

   Författare :Rebecka Arnsrud Godtman; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; active surveillance; age; cause of death; opportunistic; organized; overdiagnosis; prostate cancer; prostate-specific antigen; risk factors; screening; screening interval;

   Sammanfattning : The overall aim of this thesis is to explore aspects of overdiagnosis, i.e. the diagnosis of a tumor that in the absence of screening would never have been diagnosed, in prostate cancer (PC) screening. LÄS MER

3. 12. Molecular Genetic Studies on Prostate and Penile Cancer

   Författare :Patiyan Andersson; Peter Söderkvist; Mattias Höglund; Linköpings universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Prostate cancer; IRS1; penile cancer; hTERT; FHIT; PIK3CA; HRAS; KRAS; NRAS; BRAF; Oncology; Onkologi;

   Sammanfattning : This thesis is comprised of two parts. In the first part we study the influence of four frequently disputed genes on the susceptibility for developing prostate cancer, and in the second part we attempt to establish a basic understanding of the molecular genetic events in penile cancer. LÄS MER

4. 13. Role of Wnt5a in Prostate Cancer

   Författare :Azharuddin Sajid Syed Khaja; Malmö Urologisk cancerforskning; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Prostate Cancer; Wnt5a; tissue micro array; Biochemical recurrence; Gene fusions;

   Sammanfattning : Wnt5a is a non-canonical secreted glycoprotein of the Wnt family that plays important roles in organ development and tissue orientation. Previous studies have reported that Wnt5a was upregulated at both mRNA and protein levels in prostate cancer, but information regarding its role in predicting clinical outcome in patients after radical prostatectomy is limited. LÄS MER

5. 14. Clinical Aspects of Hereditary Breast Cancer

   Författare :Niklas Loman; Bröstcancer-genetik; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cancer; Cytologi; onkologi; cancerology; oncology; Cytology; Age of onset; Survival analysis; Incidence; Male breast cancer; Steroid receptors; BRCA2; BRCA1; Breast cancer; hereditary;

   Sammanfattning : A positive family history of breast cancer (BC) is one of the strongest predictors of the disease. Two major BC susceptibility genes, BRCA1 and BRCA2 were identified about a decade ago. In this thesis, studies of different biological. clinical and epidemiological aspects of hereditary BC are presented. LÄS MER

7. 15. Aspects of Chemotherapy in Prostate Cancer

   Författare :Åsa Jellvert; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; prostate cancer; CRPC; chemotherapy; metronomic; prognostic; predictive; biomarkers;

   Sammanfattning : Since 2004 chemotherapy has been a part of standard of care in prostate cancer (PC) and improved symptom control and survival has been demonstrated in metastatic castration-resistant PC. Whether docetaxel has benefits in earlier stages of PC is currently under investigation. LÄS MER