Sökning: "Proline dehydrogenase"

Visar resultat 1 - 5 av 6 avhandlingar innehållade orden Proline dehydrogenase.

  1. 1. The Role of Proline Catabolism in Candida albicans Pathogenesis

    Författare :Fitz Gerald S. Silao; Per O. Ljungdahl; Joachim Morschhäuser; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Candida albicans; proline metabolism; ATP; P5C; virulence; macrophage; hyphae; filamentation; Ras1 cAMP PKA; mitochondria; Proline dehydrogenase; P5C dehydrogenase; reactive oxygen species; Proline-P5C cycle; molekylär biovetenskap; Molecular Bioscience;

    Sammanfattning : Candida albicans is an opportunistic fungal pathogen that has evolved in close association with human hosts. Pathogenicity is linked to an array of virulence characteristics expressed in response to environmental cues and that reflect the requirement to take up and metabolize nutrients available in the host. LÄS MER

  3. 2. Structural and mechanistic aspects of alcohol dehydrogenase function

    Författare :Stefan Svensson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Vertebrates possess a complex alcohol dehydrogenase (ADH) system composed of multiple molecular forms, which are currently classified into seven classes according to their structural properties. ADHs are dimeric zinc metalloenzymes that catalyze the reversible oxidation of alcohols to aldehydes/ketones using NAD+/NADH as electron acceptor and donor, respectively. LÄS MER

  4. 3. Retinoid processing in vivo : characterization and structure-function analysis of retinol dehydrogenases

    Författare :Kristian Tryggvason; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Retinol; vitamin A; retinol dehydrogenase; reporter assay;

    Sammanfattning : Retinoids (vitamin A derivatives) are vital nutrients that regulate a variety of physiological processes, including embryonic development, postnatal growth, reproduction, cell differentiation as well as maintenance of the immune system and vision. Most of the physiological functions of retinoids are believed to be controlled by retinoic acid (RA) altered gene expression via two classes of nuclear hormone receptors, the RARs and RXRs. LÄS MER

  5. 4. Nitrogen and Redox Metabolism in Saccharomyces cerevisiae

    Författare :Eva Albers; Chalmers tekniska högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Saccharomyces cerevisiae; glutamate; protein expression; anaerobic physiology; nitrogen metabolism; redox; serine;

    Sammanfattning : Anaerobic conversion of glucose to ethanol by the yeast Saccharomyces cerevisiae has been studied. Glycerol is formed as a by-product in order to maintain the overall redox balance. LÄS MER

  7. 5. Skeletal muscle HIF-1 and exercise

    Författare :Helene Rundqvist; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Regular physical activity prevents and improves a number of disease conditions and reduces the risk for premature death substantially. From a clinical as well as a basic science point of view it is important to create a more fundamental understanding of the molecular mechanisms that contribute to the improved functional capacity induced by regular physical activity. LÄS MER