Sökning: "Prolactin-transgenic"

Hittade 2 avhandlingar innehållade ordet Prolactin-transgenic.

1. 1. Molecular characterization of prostate hyperplasia in prolactin transgenic mice

   Författare :Karin Dillner; Göteborgs universitet; []
   Nyckelord :Prolactin-transgenic; mouse; prolactin; prostate hyperplasia; gene expression analysis;

   Sammanfattning : Benign prostatic hyperplasia (BPH) and prostate cancer are age-related diseases, affecting a majority of elderly men in the western world, and are known to be influenced by several different hormones, including sex hormones. Although the hormone prolactin (PRL) is well known to exert trophic effects on prostate cells, its involvement in the pathophysiology is still poorly characterized. LÄS MER

3. 2. Effects of prolactin on metabolism - changes induced by hyperprolactinemia

   Författare :Louise Nilsson; Göteborgs universitet; []
   Nyckelord :prolactin; prolactin receptor; hyperprolactinemia; adipose tissue; lipoprotein lipase; malonyl-CoA; glucose transporter 4; retinol-binding protein 4; adiponectin; lipid oxidation;

   Sammanfattning : High prolactin levels during breast-feeding, is recognized to influence metabolism in order to supply glucose and fat for milk production. Pathologic overproduction of prolactin, hyperprolactinemia, is a condition primarily associated with reproductive disorders; however, the metabolic impact of elevated prolactin indicates that these parameters might be considered in clinical management of the condition. LÄS MER