Sökning: "Prokaryoter"

Hittade 4 avhandlingar innehållade ordet Prokaryoter.

  1. 1. Adaptations and constraints associated with autotrophy in microbial metabolism

    Författare :Johannes Asplund Samuelsson; Elton P. Hudson; Adil Mardinoglu; Costas D. Maranas; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Autotrophy; Carbon fixation; CO2 fixation; Calvin cycle; CBB cycle; Bacteria; Archaea; Prokaryotes; Cyanobacteria; Synechocystis; E. coli; Comparative genomics; Metabolic engineering; Microbial metabolism; Machine learning; Systems biology; Ribosome profiling; Kinetic modeling; Enzyme kinetics; Metabolic models; Pathway enumeration; Biosynthesis pathways; Metabolomics; Metabolite concentrations; Thermodynamics; Autotrofi; Kolfixering; CO2-fixering; Calvincykeln; CBB-cykeln; Bakterier; Arkéer; Prokaryoter; Cyanobakterier; Synechocystis; E. coli; Jämförande genomik; Metabolisk ingenjörskonst; Mikrobiell metabolism; Maskininlärning; Systembiologi; Ribosomprofilering; Kinetisk modellering; Enzymkinetik; Metaboliska modeller; Syntesvägsuppräkning; Biosyntesvägar; Metabolomik; Metabolitkoncentrationer; Termodynamik; Bioteknologi; Biotechnology;

    Sammanfattning : Carbon dioxide (CO2) emissions from human activities are driving climate change, but the pending crisis could be mitigated by a circular carbon economy where released CO2 is recycled into commodity chemicals. Autotrophic microbes can make a contribution by producing chemicals, such as biofuels, from CO2 and renewable energy. LÄS MER

  3. 2. From genes to blooms : Diversity in microcystin phenotypes and mcy biosynthesis genes in the cyanobacterium Microcystis

    Författare :Emma Johansson; Enhet akvatisk ekologi; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; limnologi; algblomning; cyanobakterier; cyanotoxiner; limnology; cyanobacterial blooms; cyanotoxins;

    Sammanfattning : Cyanobacterial blooms are increasing in occurrence and frequency world-wide, mainly due to eutrophication and increased water temperatures. In freshwater, Microcystis is one of the most common bloom-forming genera, renowned for producing the toxin microcystin which is harmful to humans and other mammals. LÄS MER

  4. 3. On the antiporter-like subunits of respiratory chain Complex I - implications for the evolution and coupling mechanism of the NADH:quinone oxidoreductase enzyme complex

    Författare :Cecilie Mathiesen; Biokemi och Strukturbiologi; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Metabolism; Biokemi; metabolism; Biochemistry; mrp; electron transport; respiration; membrane protein;

    Sammanfattning : Complex I or NADH:quinone oxidoreductase is the largest enzyme complex, but the least understood energy coupling site in the respiratory chain of mitochondria and bacteria. No high-resolution structural information exists for this enzyme and the molecular mechanism that couples electron transfer and proton pumping is not understood. LÄS MER

  5. 4. Nucleic Acids as Drug Targets -Interactions of Platinum Complexes, Polyamines, and siRNA with DNA and RNA Models

    Författare :Margareta Hägerlöf; Biokemi och Strukturbiologi; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Kinetics; Kemi; Chemistry; AU-rich region; siRNA; Circular Dichroism; Polyamine; Modified Nucleoside; HPLC; Thermodynamic Stability; cisplatin; Hairpin; DNA and RNA conformation; RNA; DNA; Anticancer Drug; Platinum Complexes;

    Sammanfattning : Drugs targeting nucleic acids were studied in DNA and RNA model systems. The effects were investigated with respect to structural and thermodynamic influence, kinetics, and biological function. The drugs employed in this thesis were anticancer active platinum(II) complexes, polyamine derivatives, and siRNA. LÄS MER