Sökning: "Proinflammatory cytokines"

Visar resultat 21 - 25 av 179 avhandlingar innehållade orden Proinflammatory cytokines.

  1. 21. Neurocognitive and endocrine dysfunction in women with exhaustion syndrome

    Författare :Agneta Sandström; Tommy Olsson; Lars Nyberg; Marie Åsberg; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cognition; attention; working memory; exhaustion syndrome; major depression; cortisol; HPA-axis; proinflammatory cytokines; psychology; neurocognitive; endocrine; fMRI; MRI; prefrontal cortex; multivariate; women; personality; TCI; stress; Public health medicine research areas; Folkhälsomedicinska forskningsområden; Diagnostic radiology; Diagnostisk radiologi; medicin; Medicine; diagnostisk radiologi; Diagnostic Radiology;

    Sammanfattning : Stress has emerged as one of the most important factors to consider in psychiatric diagnoses and has become a common reason for long-term sick leave (LTSL). Roughly 50% of LTSL due to psychiatric diseases are thought to be associated with work-related stress. LÄS MER

  3. 22. Cytokines and cytokine-directed intervention in experimental arthritis

    Författare :Karin Palmblad; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :pro-inflammatory cytokines; collagen-induced arthritis; CNI-1493; HMG-1;

    Sammanfattning : Rheumatoid arthritis (RA) is a common chronic autoimmune and inflammatory disease. Although the etiology of RA remains unknown, a general understanding of the pathogenesis is steadily increasing. The macrophage products tumor necrosis factor (TNF) and interleukin 1 (IL-1) are recognized as pivotal mediators in the arthritic process. LÄS MER

  4. 23. HMBG1 as a proinflammatory mediator in arthritis

    Författare :Riikka Kokkola; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Proinflammatory cytokines are central in the pathogenesis of chronic arthritis and a new generation of therapeutics blocking TNF or IL-1 has improved outcome for many patients with inflammatory joint diseases. This thesis addresses the role of HMGB1 (High Mobility Group Box Chromosomal protein 1) in inflammation and as a potential novel therapeutic target molecule in arthritis. LÄS MER

  5. 24. Inflammatory cytokines and NFκB in Alzheimer’s disease

    Författare :Linda Fisher; Kerstin Iverfeldt; Illana Gozes; Stockholms universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; β-amyloid; interleukin-1; interleukin-6; cell-penetrating peptide; PNA; Neurochemistry; Neurokemi;

    Sammanfattning : Alzheimer’s disease is the most common form of dementia. It is a neurodegenerative disorder characterized by extracellular senile plaques and intracellular neurofibrillary tangles. The main constituent of the senile plaques is the neurotoxic β-amyloid peptide. LÄS MER

  7. 25. Calcium metabolism and cytokines in critical illness

    Författare :Fredrik Carlstedt; Uppsala universitet; []
    Nyckelord :Medical sciences; calcium; critical illness; hemodynamics; hypocalcemia; IL-6; mortality; TNF-alpha; severity of disease; sepsis; MEDICIN OCH VÅRD; MEDICINE; MEDICIN; Medicine; medicin;

    Sammanfattning : Hypocalcemia is a common finding in critically ill patients, particularly in those with sepsis, and has been found to be associated with increased mortality. The pathogenesis of this altered calcium metabolism is unknown and the effects of calcium supplementation are poorly investigated. LÄS MER