Sökning: "Progestins"

Visar resultat 1 - 5 av 12 avhandlingar innehållade ordet Progestins.

  1. 1. Progestagenic Aquatic Contaminants Act as Potent Androgens in Fish : Experimental Studies in Three-spined Stickleback and Zebrafish

    Författare :Johan Svensson; Björn Brunström; Ingvar Brandt; Ian Mayer; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Pharmaceuticals as contaminants; Progestins; Androgenic properties; Fish; Biologi med inriktning mot ekotoxikologi; Biology with specialization in Environmental Toxicology;

    Sammanfattning : The extensive use of pharmaceuticals and their poor removal by wastewater treatment plants has led to the emergence of pharmaceutical compounds as global aquatic contaminants. Progestins, the synthetic analogues to progesterone (P4), are receiving increasing attention as contaminants and have been shown to impair reproduction in fish and amphibians at low ng L-1 concentrations. LÄS MER

  3. 2. Hormone replacement therapy and effects on mood

    Författare :Inger Björn; Inger Sundström-Poromaa; Torbjörn Bäckström; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; adverse effects; estradiol; hormone replacement therapy HRT ; mood; negative side effects; progestins;

    Sammanfattning : Background: During the past 5 decades, hormone replacement therapy (HRT) has been used, and appreciated for its beneficial effects, by millions of women in their menopause. As treatment for climacteric symptoms, estrogen is outstanding, and effects on hot flushes, vaginal dryness, and insomnia have been widely documented. LÄS MER

  4. 3. Some hormonal factors in the etiology of endometrial cancer

    Författare :Elisabete Weiderpass; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Endometrial neoplasms; hormone replacement therapy; estrogens; progestins; contraceptive agents; organochlorines; pesticides; polychlorinated biphenyls; estrogen receptor alfa polymorphisms;

    Sammanfattning : The main purpose of this dissertation was to study the impact of some hormone-related factors in the etiology of endometrial neoplasms, i.e. hormone replacement therapy, use of oral contraceptives, serum levels of 20 different organochlorine substances, and polymorphisms in the estrogen receptor alpha (ER) gene. LÄS MER

  5. 4. An epidemiologic study of epithelial ovarian malignancies : with a focus on hormone-related factors

    Författare :Tomas Riman; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Epithelial ovarian cancer; borderline ovarian tumors; epidemiology; risk factors; reproductive history; oral contraceptives; hormone replacement therapy; estrogens; progestins; case-control studies.;

    Sammanfattning : The main purpose of this thesis was to examine estrogen and progestin effects of hormone replacement therapy, in relation to the risk for epithelial ovarian neoplasias. Other intentions were to assess reproductive factors, oral contraceptive use, previous gynecologic surgeries, and family history of ovarian cancer according to the risk of ovarian neoplasias, and to connect these findings to different hypotheses regarding ovarian carcinogenesis. LÄS MER

  7. 5. Androgenic Effects of the Progestin Levonorgestrel in Three-spined Stickleback (Gasterosteus aculatus)

    Författare :Johan Svensson; Björn Brunström; Ingvar Brandt; Emma Wincent; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Biologi med inriktning mot ekotoxikologi; Biology with specialization in Environmental Toxicology;

    Sammanfattning : The extensive use of pharmaceuticals and their poor removal by wastewater treatment plants has led to the emergence of pharmaceutical compounds as global aquatic contaminants. Progestins, the synthetic analogues to progesterone, are receiving increasing attention as contaminants and have been shown to impair reproduction in fish and amphibians at low ng L-1 concentrations. LÄS MER