Sökning: "Progenitor cells"
Visar resultat 1 - 5 av 365 avhandlingar innehållade orden Progenitor cells.
1. Characterization of Retinal Progenitor Cells : Focus on Proliferation and the GABAA Receptor System
Sammanfattning : One strategy to repair an injured or degenerated retina is to stimulate the replacement of damaged or dead neurons with cells derived from endogenous stem- or progenitor cells. A successful strategy requires knowledge about how the proliferation and differentiation of the endogenous cells are regulated. LÄS MER
Sammanfattning : Neuronal loss is a common feature of many neurological disorders, including stroke, Parkinson’s disease, Alzheimer’s disease and traumatic brain injury. Human embryonic stem cells (hESCs) and hESC-derived neural progenitors (NPs) may provide a number of new ways for studying and treating diseases and injuries in the brain. LÄS MER
3. Progenitor cells in the postnatal central nervous system, characterization and genetic manipulation
Sammanfattning : New neurons are only generated in two places of the postnatal brain; the subventricular zone (SVZ) and hippocampus. The SVZ-derived cells specifically migrate to the olfactory bulb where they give rise to new interneurons. LÄS MER
Sammanfattning : More than 90% of DNA does not code for proteins and for a long time these sequences were referred to as “junk DNA” due to their unknown purpose. With the advent of new technologies it is now known, that the non-coding part of the genome is of great importance for regulating gene expression and is therefore indispensable. LÄS MER
5. Auxiliary Cells for the Vascularization and Function of Endogenous and Transplanted Islets of Langerhans
Sammanfattning : Type 1 diabetes develops through the progressive destruction of the insulin-producing beta-cells. Regeneration or replacement of beta-cells is therefore needed to restore normal glucose homeostasis. Presently, normoglycemia can be achieved by the transplantation of whole pancreas or isolated islets of Langerhans. LÄS MER