Sökning: "Predictive Design Analysis"

Visar resultat 1 - 5 av 91 avhandlingar innehållade orden Predictive Design Analysis.

  1. 1. Fundamentals of a Methodology for Predictive Design Analysis

    Författare :Martin Eriksson; Produktutveckling; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Predictive design analysis; Generic design analysis process model; Confidence appraisal activities; Computer-based design analysis; Engineering design; Integration;

    Sammanfattning : The rapid development of computer-based design analysis tools and methods such as the finite element method (FEM) within computational structural mechanics (CSM), computational fluid dynamics (CFD), and multi-body systems (MBS) during recent decades has fundamentally changed the way in which products are designed and developed. Among the many advantages observed in industrial practice, one can mention improved understanding of product properties and behavior, the possibility to optimize critical design parameters and to optimize parts as well as the entire product at a system level, the possibility to explore a design space during the synthesis activity, and a decrease of the need for physical testing and thus of the number of physical prototypes needed. LÄS MER

  2. 2. Finite Element Analysis and Design of Experiments in Engineering Design

    Författare :Martin Eriksson; Produktutveckling; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Finite element analyses; Predictive Design Analysis; Mechanical engineering design process; Design Of Experiments; Predictive Engineering;

    Sammanfattning : Projects with the objective of introducing Finite Element Analysis (FEA) into the early phases of the design process have previously been carried out at the Department of Machine Design, see e.g. the Doctoral thesis by Burman [13]. These works clearly highlight the usefulness of introducing design analysis early in the design process. LÄS MER

  3. 3. Mapping the consequenses of physical exercise and nutrition on human health : A predictive metabolomics approach

    Författare :Elin Chorell; Henrik Antti; Lorraine Brennan; Umeå universitet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Metabolomics; physical exercise; cardiorespiratory fitness nutrition; high protein and fat diet; Lactobacillus F19; probiotics; GC-MS; plasma; chemometrics; multivariate analysis statistical experimental design; design of experiments; Chemistry; Kemi; Systems Analysis; systemanalys; näringslära; Nutrition; molecular medicine medical sciences ; molekylär medicin medicinska vetenskaper ;

    Sammanfattning : Human health is a complex and wide-ranging subject far beyond nutrition and physical exercise. Still, these factors have a huge impact on global health by their ability to prevent diseases and thus promote health. LÄS MER

  4. 4. Benefits of Pharmacometric Model-Based Design and Analysis of Clinical Trials

    Författare :Kristin E Karlsson; E Niclas Jonsson; Mats O Karlsson; Anders Grahnén; Michael K Smith; Uppsala universitet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; model-based analysis; pharmacometrics; modeling; disease progression; NONMEM; SAEM; Importance sampling; repeated time-to-event; RTTCE; RCEpT; NIH stroke scale; Barthel index; internal validation; external validation; study power; study design; PHARMACY; FARMACI; Pharmacokinetics and Drug Therapy; Farmakokinetik och läkemedelsterapi;

    Sammanfattning : Quantitative pharmacokinetic-pharmacodynamic and disease progression models are the core of the science of pharmacometrics which has been identified as one of the strategies that can make drug development more effective. To adequately develop and utilize these models one needs to carefully consider the nature of the data, choice of appropriate estimation methods, model evaluation strategies, and, most importantly, the intended use of the model. LÄS MER

  5. 5. Model-based Analysis and Design of Atomic Layer Deposition Processes

    Författare :Anders Holmqvist; Institutionen för kemiteknik; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Atomic layer deposition; Heterogeneous reaction kinetics; Limit-cycle dynamics; Parameter estimation; Multi-objective optimization; Dynamic optimization; Scale-up analysis;

    Sammanfattning : Atomic layer deposition (ALD) is a thin-film manufacturing process in which the growth surface is exposed to non-overlapping alternating injections of gas-phase chemical precursor species separated by intermediate purge periods to prevent gas-phase reactions. ALD is characterized by sequential self-terminating heterogeneous reactions between highly reactive gas-phase precursor species and surface-bound species which, when allowed sufficient conditions to reach saturation, results in highly conformal films, on both planar and topographically complex structures. LÄS MER