Sökning: "Pre-mRNA processing"
Visar resultat 1 - 5 av 18 avhandlingar innehållade orden Pre-mRNA processing.
1. The SWI/SNF complex : Roles in transcription and pre-mRNA processing
Sammanfattning : The regulation of gene expression is fundamental to the development of complex organisms and an important driving force in this process. When and where the genes are expressed decide the fate of a cell and its physiological context in the organism. LÄS MER
2. Biochemical and structural studies of pre-mRNA splicing
Sammanfattning : When eucaryotic genes are expressed, they are transcribed into pre-mRNAs (precursor mRNAs) that need extensive processing before they can be exported from the nucleus as mRNAs and translated into proteins in the cytoplasm. One central processing event is splicing, which means removal of intervening, non-coding sequences, introns and joining of functional sequences, exons. LÄS MER
3. Pre-mRNA processing in the polytene nuclei of chironomus tentans
Sammanfattning : Gene expression of protein encoding genes in eukaryotic cells requires extensive intranuclear maturation processing of the transcribed pre-mRNA. Three such processes are known to occur. The 5' end is capped and the 3' end is determined by cleavage and polyadenylation. LÄS MER
4. ATPase dependent and independent roles of Brahma in transcription and pre-mRNA processing
Sammanfattning : SWI/SNF is a chromatin-remodeling complex and Brahma (BRM) is the ATPase subunit of SWI/SNF. BRM regulates transcription by remodeling the nucleosomes at promoter regions. BRM is also associated with RNA and affects pre-mRNA processing together with other SWI/SNF subunits. LÄS MER
5. Molecular Cloning and Functional Characterization of Factors Involved in Post-transcriptional Gene Expression
Sammanfattning : Gene expression in the eukaryotic cell is a fundamental cellular process, which consists of several distinct steps but extensively coupled to each other. From site of transcription in the nucleus to the cytoplasm, both mRNA and rRNA are associated with a proper set of proteins. LÄS MER