Sökning: "Posttranslation protein processing"

Hittade 1 avhandling innehållade orden Posttranslation protein processing.

1. 1. Proislet Amyloid Polypeptide (proIAPP) : Impaired Processing is an Important Factor in Early Amyloidogenesis in Type 2 Diabetes

   Författare :Johan F. Paulsson; Gunilla Westermark; Christer Betsholtz; Linköpings universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biosynthesis amyloid; Genetics amyloid; Metabolism amyloid; Islets of Langerhans; Proprotein convertases; Posttranslation protein processing; Medical cell biology; Medicinsk cellbiologi;

   Sammanfattning : Amyloid is defined as extracellular protein aggregates with a characteristic fibrillar ultra-structure, Congo red affinity and a unique x-ray diffraction pattern. At present, 25 different human amyloid fibril proteins have been identified, and amyloid aggregation is associated with pathological manifestations such as Alzheimer’s disease, spongiform encephalopathy and type 2 diabetes. LÄS MER