Sökning: "Post-Translational"
Visar resultat 1 - 5 av 206 avhandlingar innehållade ordet Post-Translational.
1. Compact-disc microfluidic methods for characterization of therapeutic antibodies : Analysis of post-translational modifications
Sammanfattning : Characterization of post-translational modifications (PTMs) of therapeutic proteins is very important during the bioprocess development to maintain desired product quality and during the submission process to regulatory authorities for product approval. Monitoring glycosylation in pharmacokinetic studies can be useful to evaluate the dependence of clearance rates on different glycoforms. LÄS MER
2. Post-translational modifications of eukaryotic protein synthesis elongation factor-2 : a study in relation to ageing
Sammanfattning : .... LÄS MER
3. Regulation of TGF-β Signaling by Post-Translational Modifications
Sammanfattning : Transforming growth factor-β (TGF-β) signaling is initiated when the ligand binds to type II and type I serine/threonine kinase receptors at the cell surface. Activated TGF-β type I receptors phosphorylate R-Smads which relocate, together with co-Smads, to the cell nucleus and regulate transcription. LÄS MER
4. Systems biology techniques show high prevalence of post-translational regulation in the cyanobacterium Synechocystis PCC 6803
Sammanfattning : Earth's climate has been upset by carbon dioxide (CO2) emissions from human activities and the use of fossil resources. To prevent catastrophic events on the environment and on civilizations, we urgently need to develop alternative solutions that utilize renewable resources. LÄS MER
5. Post-translational modifications in DNA base excision repair : The roles of CK2 and PARP-1
Sammanfattning : Base lesions and DNA single-strand breaks (SSBs) are very common types of DNA damage. The base excision repair (BER) and single-strand break repair (SSBR) machineries both require a succession of enzymatic events in order to remove these types of endogenous lesions and to restore the DNA. LÄS MER