Sökning: "Polysaccharide vaccine"

Visar resultat 16 - 20 av 28 avhandlingar innehållade orden Polysaccharide vaccine.

1. 16. Streptococcus pneumoniae : epidemiological, clinical and serological studies

   Författare :Lars Å. Burman; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Streptococcus pneumoniae; incidence; predisposing factors; prognosis; serotyping; etiology of pneumonia; diagnostic methods; COA; CIE; pneumococcal serology;

   Sammanfattning : A retrospective study of invasive pneumococcal disease in patients from Greater Göteborg in 1964- 1980 identified 125 cases of meningitis, 305 of pneumonia, 61 of septicemia with unknown focus, and 17 with other manifestations, all verified by cultures from normally sterile body fluids. The incidence was several times higher in infants and in the elderly than in any other age-group. LÄS MER

3. 17. Structural and Conformational Analysis of Bacterial Polysaccharides using NMR Spectroscopy

   Författare :Axel Furevi; Göran Widmalm; Corine Sandström; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Organic Chemistry; organisk kemi;

   Sammanfattning : Carbohydrates is one of the three classes of biomolecules found in nature. It is the most common one in comparison to the other two classes, lipids and proteins. However, this simple categorization does not reflect the reality since carbohydrates often are covalently linked to e.g. LÄS MER

4. 18. Invasive Pneumococcal Infections

   Författare :Erik Backhaus; Göteborgs universitet; []
   Nyckelord :Streptococcus pneumoniae; epidemiology; risk factors; pneumonia; meningitis; serotype; clonal complex;

   Sammanfattning : Streptococcus pneumoniae is a major cause of disease, ranging from uncomplicated respiratory infections to severe invasive pneumococcal disease (IPD), including bacteraemic pneumonia, septicaemia with unknown focus and meningitis. Case fatality rate (CFR) remains high and antibiotic resistance is increasing globally. S. LÄS MER

5. 19. Treatment of arthritis with tumour necrosis factor antagonists. Clinical, immunological and biochemical aspects

   Författare :Meliha C Kapetanovic; Reumatologi och molekylär skelettbiologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Skelett; muskelsystem; reumatologi; Skeleton; muscle system; rheumatology locomotion; ANA; infusion reaction; influenza vaccination; pneumococcal vaccination; COMP; TNF antagonists; spondylarthropathies; arthritis; rheumatoid arthritis;

   Sammanfattning : Abstract The treatment of arthritis has undergone a dramatic change since biological agents targeting specific mediators of the disease process have been introduced. Tumour necrosis factor (TNF) antagonists have been shown to reduce signs and symptoms of disease and to retard the development of tissue damage in the majority of patients. LÄS MER

7. 20. Synthesis of Bacterial Oligosaccharides from N. meningitidis and Mechanistic Details of Stereoselective Glycosylations Using a Novel Bicyclic Donor

   Författare :Johan Olsson; Stefan Oscarson; Jeroen Codée; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; oligosaccharide synthesis; heptose; thioglycoside; glycosylation; Neisseria meningitidis; 2; 3-oxazolidinone; Organic chemistry; Organisk kemi; organisk kemi; Organic Chemistry;

   Sammanfattning : This thesis includes two parts. The first part, comprising Chapters 3, 4 and 5, describes the synthesis of bacterial oligosaccharides. In Chapters 3 and 4, the synthesis of branched and phosphorylated oligosaccharide structures corresponding to inner core epitopes of the lipopolysaccharide (LPS) of the Gram-negative bacteria N. LÄS MER