Sökning: "Polysaccharide vaccine"

Visar resultat 11 - 15 av 28 avhandlingar innehållade orden Polysaccharide vaccine.

  1. 11. Infectious immunity and pneumococcal vaccine responses in multiple myeloma and related disorders

    Författare :Johanna Karlsson; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; multiple myeloma; Waldenstrom s macroglobulinemia; MGUS; elderly; immunity; infection; pneumococcal vaccination; ELISA; opsonophagocytosis;

    Sammanfattning : Multiple myeloma (MM), Waldenstrom’s macroglobulinemia (WM), and monoclonal gammopathy of undetermined significance (MGUS) are B cell conditions associated with suppressed immune functions and susceptibility to infection. Severe pneumococcal disease is common not least in MM patients and vaccination is considered important, although the protective efficacy is debated. LÄS MER

  3. 12. Synthesis of oligosaccharides related to the capsular polysaccharide of Neisseria meningitidis serotype A

    Författare :Peter Teodorovic; Stefan Oscarson; Mikael Elofsson; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Organic chemistry; Organisk kemi;

    Sammanfattning : In order to find suitable stable vaccine candidates against Neisseria meningitidis group A, several structures related to the capsular polysaccharide have been synthesised. The first part of the thesis describes the synthesis of C-phosphonate analogues starting from glucose. LÄS MER

  4. 13. Mechanisms for pneumococcal meningitis and a new vaccine platform to raise a serotype-independent protection in the host

    Författare :Sigrun Thorsdottir; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Streptococcus pneumoniae is a highly relevant pathogenic bacterium, responsible for a large fraction of deaths and disease morbidity in the world. The pneumococcus remains the leading cause of life-threatening pneumonia, septicemia and meningitis beyond neonatal age, despite global implementation of vaccination programs. LÄS MER

  5. 14. Infections in patients with haematological malignancies

    Författare :Honar Cherif; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Haematological malignancies; febrile neutropenia; bacteraemia; Candida; oral antibiotic; risk stratification; FUO; cefepime; splenectomy; pneumococcal vaccine;

    Sammanfattning : Infectious complications are an important cause of morbidity and mortality in patients with hematological diseases, especially during chemotherapy induced neutropenia. This study was undertaken with the ultimate goal to improve the clinical management of infections in patients with hematological diseases. LÄS MER

  7. 15. B-cell immunity in patients with hematological malignancies and after stem cell transplantation : studies with special reference to tetanus and pneumococcal immunity

    Författare :Viera Hammarström; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Treatment of malignancies with cytotoxic chemotherapy and/or bone marrow or stem cell transplantation also suppress the immune system which becomes incapable of controlling infections. Therefore infections can remain a serious problem for an extended period in these patients. LÄS MER