Sökning: "Polymorphisms"

Visar resultat 11 - 15 av 557 avhandlingar innehållade ordet Polymorphisms.

  1. 11. Plant foods, plasma enterolactone and breast cancer - with a focus on estrogen receptor status and genetic variation

    Författare :Emily Sonestedt; Diabetes - kardiovaskulär sjukdom; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; plant foods; breast cancer; fibre; epidemiology; lignans; enterolactone; plasma; estrogen receptor α; estrogen receptor β; polymorphisms; reliability; nutrition; prospective;

    Sammanfattning : Diets high in fibre have previously been associated with decreased risk of breast cancer in the Malmö Diet and Cancer cohort. Several potent compounds may exist in high-fibre diets that might protect against breast cancer, for example lignans. LÄS MER

  3. 12. ENVIRONMENTAL CONTAMINANTS AND SPERM Y:X CHROMOSOME RATIO. Impact of androgen- and dioxin-related effects in vivo and in vitro

    Författare :Tarmo Tiido; Malmö Reproduktionsmedicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; AR; polymorphisms; Sertoli cell; endocrine disruption; inhibitory cross-talk; Biomedicinska vetenskaper; Biomedical sciences; AHR; sperm Y:X chromosome ratio; sex ratio; POPs; TCDD;

    Sammanfattning : During the last decades, there has been concern that the environmental contaminants, such as POPs, may contribute to sex ratio changes in offspring of exposed populations. Accidental exposure to TCDD has been shown to be associated with fewer sons in men who were exposed in adolescence or earlier in life. LÄS MER

  4. 13. Prediction Models and Pharmacogenomics in Adult Growth Hormone Deficiency

    Författare :Edna J L Barbosa; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; growth hormone deficiency; hypopituitarism; growth hormone replacement therapy; prediction models; candidate gene approach; polymorphisms; body composition; growth hormone receptor; lipid metabolism; extracellular water; pharmacogenomics;

    Sammanfattning : The overall aim of this thesis was to study clinical and genetic factors that influence response to growth hormone replacement therapy (GHRT) in GH deficient (GHD) adults. The patients were part of a cohort of adults with hypopituitarism and severe GHD who were studied before and after 12 months of GHRT. LÄS MER

  5. 14. On Neuroimmunology and Brain Function: Experimental and Clinical Studies

    Författare :Nina Strenn; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; immune system; mental disorders; polymorphisms; depression; autism; bipolar disorder; SSRI; S100B; 5-HTR2A; Flinders sensitive line;

    Sammanfattning : The immune system has been implicated in the mechanisms underlying many psychiatric disorders. Immune mediators are expressed in the central nervous system (CNS) not only in response to harmful stimuli, but also in a constitutive manner, and serve as important plasticity factors during development. LÄS MER

  7. 15. Hereditary risk factors for stroke in humans - Association studies with emphasis on familial and genotypic factors

    Författare :Håkan Lövkvist; Lund Neurologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; allelic association; candidate genes; case-control; family history; ischemic stroke; polymorphisms.;

    Sammanfattning : Background Stroke is a serious vascular disorder that comprises intracerebral hemorrhages, subarachnoid hemorrhages and ischemic stroke (IS). The etiology of stroke, including hereditary components induced by cellular mechanisms, is therefore a research field of vital importance. LÄS MER