Sökning: "Polymorphism"

Visar resultat 6 - 10 av 689 avhandlingar innehållade ordet Polymorphism.

  1. 6. Studies on class II genes of the human major histocompatibility complex with special regards to structure : polymorphism and evolution

    Författare :Ann-Kristin Jonsson; Uppsala universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : .... LÄS MER

  3. 7. THE ANDROGEN RECEPTOR GGN POLYMORPHISM. Genetic and functional analyses

    Författare :Kristina Lundin; Avdelningen för klinisk genetik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicine human and vertebrates ; Functional domain; Genetic predisposition; Reproductive function; Sex hormone; Transactivation function; Repeat; Polymorphism; Androgen receptor; Transcription factor; Medicin människa och djur ; Endocrinology; secreting systems; diabetology; Endokrinologi; sekretion; diabetologi;

    Sammanfattning : Male sex development and reproductive function is regulated by androgens acting via the androgen receptor (AR). The AR harbours two polymorphic repeats of CAG and GGN triplets, encoding glutamines and glycines, respectively. LÄS MER

  4. 8. Investigating polymorphism in small molecules using three-dimensional electron diffraction

    Författare :Molly Lightowler; Xiaodong Zou; Hosea M. Nelson; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; 3D electron diffraction; structure determination; polymorphism; crystallisation; phase identification; small molecule; oorganisk kemi; Inorganic Chemistry;

    Sammanfattning : For scientific, regulatory and intellectual property reasons, the discovery and characterisation of polymorphic systems is an integral aspect of the development process of any solid-formulated drug product. Yet, these studies are often hindered by crystal quality and size, poor yields and the generation of mixtures of phases. LÄS MER

  5. 9. Polymorphism in sex steroid-related genes. Effects on hormone levels and behavior

    Författare :Lars Westberg; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; sex steroids; androgen receptor; estrogen receptor; progesterone receptor; polymorphism; genetics; association study; prolactin; personality; premenstrual dysphoric disorder; Parkinson s disease;

    Sammanfattning : Genetic factors are important for variations between individuals with respect to most humantraits and diseases. Sex steroids are of profound importance for reproduction, metabolism,cardiovascular function and bone formation. They are potent regulators of their ownsynthesis as well as of that of other hormones, including prolactin. LÄS MER

  7. 10. On the origin of polymorphism - consequences of competition and predation in heterogeneous environments

    Författare :Jennie Holmér; Biologiska institutionen; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; source-sink dynamics; predation; competition; dispersal; polymorphism; evolution; crypsis; adaptive dynamics;

    Sammanfattning : In this thesis, I have studied when an initially monomorphic population can diverge into two morphs in a heterogeneous environment. Evolution is driven by competition for resources or predation. In Paper I, we studied source-sink dynamics during evolution in an environment with two types of resource of different abundance in two habitats. LÄS MER