Sökning: "Poly-Glutamine"

Hittade 1 avhandling innehållade ordet Poly-Glutamine.

1. 1. Alterations in activity and specificity of intracellular proteolysis in disease pathogenesis

   Författare :Lei Lu; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Proteasome; Ubiquitin; Cancer; Neuro-degeneration; Poly-Glutamine; Apoptosis; Tripeptidyl-Peptidase II; Stress; IAP;

   Sammanfattning : The ubiquitin-proteasome pathway (UPP) plays a fundamental role in many basic cellular processes. Virtually all events in cellular physiology include control by the ubiquitin-proteasome pathway. Ubiquitinated substrates are degraded by the 26S proteasome, a large multicatalytic protease complex. LÄS MER