Sökning: "Poly lactide-co-glycolide"

Visar resultat 1 - 5 av 12 avhandlingar innehållade orden Poly lactide-co-glycolide.

  1. 1. Poly(Lactide-co-Glycolide) in Controlled-Release Pharmaceuticals - Release Mechanisms

    Författare :Susanne Fredenberg; Avdelningen för kemiteknik; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; PLGA; Poly lactide-co-glycolide ; Release mechanism; Diffusion; Controlled Release; Degradation; Protein;

    Sammanfattning : Controlled-release formulations reduce the frequency of injections and better maintain plasma concentrations within the therapeutic window. Poly(D,L-lactide-co-glycolide) (PLG) is currently the most frequently used biodegradable polymer for this application. LÄS MER

  3. 2. Covalent Surface Modification of Degradable Polymers for Increased Biocompatibility

    Författare :Martina Källrot; Ann-Christine Albertsson; Mikael Lindström; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Vapor phase grafting; covalent surface modification; solvent free; nano patterned topography; degradable polymers; poly ε-caprolactone ; poly L-lactide ; poly lactide-co-glycolide ; poly trimethylene carbonate ; N-vinylpyrrolidone; maleic anhydride; acrylamide; Gasfasympning; kovalent ytmodifiering; lösningsmedelsfri; nedbrytbara polymerer; nanomönstrad topografi; poly L-laktid ; poly ε-kaprolakton ; poly laktid-co-glykolid ; poly trimetylen karbonat ; N-vinylpyrrolidon; maleinsyraanhydrid; akrylamid; Polymer chemistry; Polymerkemi;

    Sammanfattning : Degradable polymers have gained an increased attention in the field of biomedical applications over the past decades, for example in tissue engineering. One way of improving the biocompatibility of these polymers is by chemical surface modification, however the risk of degradation during the modification procedure is a limiting factor. LÄS MER

  4. 3. Covalent Vapor-Phase Grafting of Degradable Polymers

    Författare :Martina Källrot; Ann-Christine Albertsson; Maria Nowokowska; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Vapor-phase grafting; covalent surface modification; functionalization; solvent-free grafting; sub-micron patterned topography; scaffolds; degradable polymers; poly L-lactide ; poly ε-caprolactone ; poly trimethylene carbonate ; poly L-lactide-co-glycolide ; poly 1; 5-dioxepan-2-one-co-L-lactide ; poly ε-caprolactone-co-L-lactide ; N-vinylpyrrolidone; maleic anhydride; acrylamide; acrylic acid; hyaluronic acid; in vitro degradation; Gasfasympning; kovalent ytmodifiering; funktionalisering; lösningsmedelsfri ympning; sub-micrometer mönstrad topografi; nedbrytbara polymerer; poly L-laktid ; poly ε-kaprolakton ; poly trimetylen karbonat ; poly L-laktid-co-glykolid ; poly 1; 5-dioxepan-2-one-co-L-laktid ; poly ε-kaprolakton-co-L-laktid N-vinylpyrrolidon; maleinsyraanhydrid; akrylamid; akrylsyra; hyaluronsyra; in vitro nedbrytning; Polymer chemistry; Polymerkemi;

    Sammanfattning : Gasfasympning är en del i den moderna strategin för optimering av den molekylära designen av biomaterial. Kovalent ytmodifiering med hydrofila vinylmonomerer och koppling med bioaktiva grupper används för att öka biokompatibiliteten och bioaktiviteten hos biomaterialen.. LÄS MER

  5. 4. Mass-Transport through Interfaces

    Författare :Sofie Gårdebjer; Chalmers tekniska högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; poly 3-hydroxybutyrate ; permeability; diffusion cells; poly lactide-co-glycolide acid ; mass-transport; polyethylene; poly lactic acid ; ethylene acrylic acid; interfaces; cellulose;

    Sammanfattning : Many of the products in our daily life consist of layered structures, where packaging materials and wound care products can be mentioned as examples. These structures often consist of different kind of polymeric materials and between these materials interfaces are formed. LÄS MER

  7. 5. Design of Functional Polymeric Nanoparticles for Biomedical Applications

    Författare :Heba Asem; Eva Malmström; Tim Bowden; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Biodegradable polymers; SPION; PISA; RAFT; nanoparticles; drug delivery; cytotoxicity; MRI; in vivo fluorescence imaging; Fiber- och polymervetenskap; Fibre and Polymer Science;

    Sammanfattning : Most of the devastating diseases such as cancer are relatively incurable and have high risks of relapse. Therefore, persistent endeavors have been devoted to improve patient survival rate and quality of life. LÄS MER