Sökning: "Platelet concentrate"
Visar resultat 1 - 5 av 9 avhandlingar innehållade orden Platelet concentrate.
1. Platelet activation and aggregation: Clinical and experimental studies
Sammanfattning : Background: Dual antiplatelet therapy with acetylsalicylic acid (ASA) and the adenosine diphosphate (ADP)-receptor antagonist ticagrelor increases the risk of bleeding complications during cardiac surgery. The overall aim of this thesis was to identify and evaluate current and potential methods to reduce and prevent bleeding complications in patients with ongoing antiplatelet therapy. LÄS MER
2. Platelet Inhibition and Bleeding Complications in Cardiac Surgery Patients - Clinical and experimental studies
Sammanfattning : BACKGROUND AND OBJECTIVE Dual antiplatelet therapy (DAPT) with acetylsalicylic acid and a P2Y12 inhibitor (clopidogrel, ticagrelor, or prasugrel) reduces thrombotic events in patients with acute coronary syndrome (ACS), but it is also associated with an increased risk of bleeding complications. The aim of this project was to investigate the prevalence and effects of platelet inhibition in the context of cardiac surgery, the bleeding problems that may occur, and treatment of bleeding complications. LÄS MER
3. Stimulation of tendon repair by platelet concentrate, CDMP-2 and mechanical loading in animal models
Sammanfattning : Growth factor delivery may be useful to accelerate the rate of tendon healing. We studied Platelet Concentrate, which in effect can be regarded as a cocktail of growth factors relevant for tendon healing. LÄS MER
4. The use of fibrinogen in cardiac surgery patients-clinical and experimental studies
Sammanfattning : BACKGROUND Cardiac surgery with cardiopulmonary bypass impairs hemostasis due to hemodilution and consumption of platelets and coagulation factors, such as fibrinogen. The aim of this thesis was to study the role of fibrinogen in bleeding complications in cardiac surgery patients. LÄS MER
5. A study of factors influencing the quality of blood products during preparation, storage and filtration
Sammanfattning : The quality of a cell concentrate to be transfused is dependent on the method of preparation and the storage conditions of the blood products. The aim of this study was to determine, compare and evaluate factors influencing the quality of platelet and erythrocyte concentrates. LÄS MER