Sökning: "Plaque Assay"

Visar resultat 1 - 5 av 29 avhandlingar innehållade orden Plaque Assay.

  1. 1. Effects of galectins and antibodies in HIV infection; Novel Assays

    Författare :Enas Sheik-Khalil; Institutionen för laboratoriemedicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; HIV-1; galectin-1; galectin-8; neutralizing antibodies; cell-cell fusion; Microscale anisotropy assay; virus binding assay; glycosylation; gp120; Automated plaque reduction assay; CellProfiler; NeutNet;

    Sammanfattning : The high variability of the HIV envelope glycoproteins (Env), and their heavy glycan coating, contributes to the limited host immune control. Still, broadly neutralizing antibodies (bnAbs) are found in some chronically infected HIV-infected individuals, which has spurred the research on antibody-based vaccines. LÄS MER

  3. 2. Xylitol and its effect on oral ecology : clinical studies in children and adolescents

    Författare :Pernilla Lif Holgerson; Svante Twetman; Christina Stecksén-Blicks; Eva Söderling; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; chewing gum; dental plaque; dose-response relationship; interdental plaque-pH; oral microorganisms; saliva; xylitol; Paedodontics; Pedodonti;

    Sammanfattning : Xylitol, classified as a natural sugar substitute, has for about 35 years been known as an agent that may act against caries. The mechanism of action; how it inhibits mutans streptococci (MS) and the clinical dose-response relationship are not however fully investigated. LÄS MER

  4. 3. Platelet Adhesion to Proteins in Microplates : Applications in Experimental and Clinical Research

    Författare :Andreas Eriksson; Per Whiss; Håkan Wallén; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; platelets; platelet adhesion; platelet assay; synergistic activation; thrombosis; anti-platelet treatment; Pharmacology; Farmakologi;

    Sammanfattning : Platelets are crucial for prevention of blood loss after vessel injury. Platelet adhesion to disrupted vessel walls is mediated by receptors such as the GPIb-IX-V complex that binds von Willebrand factor and the collagen-binding integrin α2β1. LÄS MER

  5. 4. Linking quantitative radiology to molecular mechanism for improved vascular disease therapy selection and follow-up

    Författare :Andrew J Buckler; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Objective: Therapeutic advancements in atherosclerotic cardiovascular disease have improved the prevention of ischemic stroke and myocardial infarction. However, diagnostic methods for atherosclerotic plaque phenotyping to aid individualized therapy are lacking. LÄS MER

  7. 5. Coreceptor usage and sensitivity to neutralization of HIV-1 and HIV-2

    Författare :Yu Shi; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :HIV-1; HIV-2; pathogenesis; neutralization; coreceptor usage; envelop sequence; glycosylation; U87.CD4 cells; GHOST 3 cells; CCR5; CXCR4;

    Sammanfattning : The aim of this project was to study neutralization and coreceptor use in HIV-1 and HIV-2. The first step was to develop a simple and standardized assay for detection and quantification of HIV- 1 neutralizing activity in human sera. LÄS MER