Sökning: "Pinar Akcakaya"

Hittade 1 avhandling innehållade orden Pinar Akcakaya.

1. 1. Molecular mechanisms of imatinib resistance in gastrointestinal stromal tumor with focus on microRNAs

   Författare :Pınar Akçakaya; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Gastrointestinal stromal tumor (GIST) is mainly initialized by mutations in receptor tyrosine kinase genes KIT or PDGFRA. The development of imatinib, a small molecule inhibitor that targets these tyrosine kinase receptors, remarkably improved patient outcome. LÄS MER