Sökning: "Physiology Fysiologi granule transport Myosin 5a Cyclic AMP NADPH Motor protein Insulin secretion Cytoskeleton"
Hittade 1 avhandling innehållade orden Physiology Fysiologi granule transport Myosin 5a Cyclic AMP NADPH Motor protein Insulin secretion Cytoskeleton.
1. Transport and release of insulin granules during biphasic insulin secretion
Sammanfattning : Glucose-evoked insulin secretion exhibits two phases: The first phase represents exocytosis of insulin granules situated at the plasma membrane, whereas the second phase reflects insulin release from granules continuously recruited to the plasma membrane. This thesis investigates different aspects of phasic insulin secretion, with the specific aims to elucidate the possible contribution of insulin granule transport, as well as to study the influence of the nucleotides cAMP and NADPH to this process. LÄS MER