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Visar resultat 6 - 10 av 26 avhandlingar som matchar ovanstående sökkriterier.

  1. 6. A biophysical study of nucleic acid interactions with analogues and drugs

    Författare :Ulrica Sehlstedt; Donald M Crothers; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Nucleic acids; binding modes; polarised light spectroscopy; linear dichroism; NMR; triple helix; base-pair breathing dynamics; DAPI; porphyrins; quinoxaline derivatives; Biophysics; Biofysik; Biophysics; biofysik;

    Sammanfattning : work presented in this thesis concerns studies on the physicochemical nature of interactions between nucleic acids and small ligands. The outcome of such studies can yield insights at a molecular level into the physiological mechanisms of action of biologically active nucleic-acid binding molecules. LÄS MER

  2. 7. How could Christmas trees remain evergreen? : photosynthetic acclimation of Scots pine and Norway spruce needles during winter

    Författare :Pushan Bag; Stefan Jansson; Fransis Andre Wollman; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Scots Pine; Norway spruce; Photosynthesis; Winter adaptation; biologisk kemi; biological chemistry; biology; biologi; molekylärbiologi; Molecular Biology; Physiological Botany; fysiologisk botanik;

    Sammanfattning : Plants and other green organisms harvest sunlight by green chlorophyll pigments and covertit to chemical energy (sugars) and oxygen in a process called photosynthesis providing the foundation for life on Earth. Although it is unanimously believed that oceanic phytoplanktons are the main contributors to the global photosynthesis, the contribution of coniferous boreal forests distributed across vast regions of the northern hemisphere cannot be undermined. LÄS MER

  3. 8. Imaging Living Cells with an X-ray Laser

    Författare :Gijs van der Schot; Tomas Ekeberg; Janos Hajdu; Filipe Maia; Pierre Thibault; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Coherent diffractive X-ray imaging; flash X-ray imaging; lensless imaging; single particle imaging; cyanobacteria; phasing; image classification; substrate-free sample delivery; X-ray free-electron laser; XFEL; FEL; CDXI; CDI; CXI; FXI; Chemistry with specialization in Biophysics; Kemi med inriktning mot biofysik;

    Sammanfattning : Imaging living cells at a resolution higher than the resolution of optical microscopy is a significant challenge. Fluorescence microscopy can achieve a degree of super-resolution via labeling cellular components with a fluorescent dye. LÄS MER

  4. 9. Fluorescence microscopy studies of interactions between monomeric α-Synuclein and lipid membranes

    Författare :Alexandra Andersson; NanoLund: Centre for Nanoscience; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Total internal reflection fluorescence microscopy; single vesicle imaging; single molecule imaging; protein-lipid interactions; α-Synuclein;

    Sammanfattning : α-Synuclein (α-Syn), is an intrinsically disordered protein present in the substantia nigra part of the brain. α-Syn is commonly known to associate with lipid membranes containing anionic lipids. LÄS MER

  5. 10. Photoluminescence-based characterization of bioengineered nanovesicles and erbium emitters

    Författare :Maryam Sanaee; Katia Gallo; Jerker Widengren; Martin Hof; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Bioengineered nanovesicles; Coincident fluorescent burst analysis; Drug loading; Erbium emitters; Lithium niobate; Photoluminescence.; Bioingenjörskonstruerade nanovesiklar; Analys av sammanfallande fluorescerande blossteknik; Läkemedelslastning; Erbium-emitterare; Lithium niobate; Fotoluminiscens.; Biologisk fysik; Biological Physics; Optics and Photonics; Optik och fotonik;

    Sammanfattning : In recent decades, photoluminescence properties of single molecules and ions have opened new possibilities for studies on smaller size scales, below the light-diffraction limit. In this thesis, the advantages of such single photon emitters were harnessed and studied mainly in the field of biophysics, but also, in investigations within solid state photonics. LÄS MER