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Visar resultat 1 - 5 av 401 avhandlingar som matchar ovanstående sökkriterier.

1. 1. Quantitative analysis of tumor growth and response to therapy

   Författare :Esmaeil Mehrara; Göteborgs universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; tumor; growth; response; therapy; modeling; clinical;

   Sammanfattning : Modeling the natural growth of tumors is of value for evaluation of tumor progression and optimization of treatment strategies. However, modeling tumor growth based on clinical data is hampered by the limited data available, since therapy is in general initiated as early as possible after diagnosis. LÄS MER

3. 2. Modelling late toxicity in hypofractionated radiation therapy

   Författare :Niclas Pettersson; Göteborgs universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Hypofractionation; normal tissue complication probability; modelling; linear-quadratic model; fractionation sensitivity; late toxicity; radiation-induced rib fracture; genitourinary toxicity; stereotactic body radiation therapy; high-dose-rate brachytherapy; multimodality radiation therapy; patient-reported outcomes; prostate cancer; nsclc;

   Sammanfattning : In hypofractionated radiation therapy (RT), the treatment is delivered by few fractions with high doses per fraction. This is in contrast to conventionally fractionated RT where the total dose is delivered in many fractions with low doses per fraction. LÄS MER

4. 3. Monte Carlo particle transport codes for ion beam therapy treatment planning : Validation, development and applications

   Författare :Till Tobias Böhlen; Irena Gudowska; Oliver Jäkel; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Monte Carlo; ion beam therapy; treatment planning; cancer therapy; microdosimetry; Medical Radiation Physics; medicinsk strålningsfysik;

   Sammanfattning : External radiotherapy with proton and ion beams needs accurate tools for the dosimetric characterization of treatment fields. Monte Carlo (MC) particle transport codes, such as FLUKA and GEANT4, can be a valuable method to increase accuracy of dose calculations and to support various aspects of ion beam therapy (IBT), such as treatment planning and monitoring. LÄS MER

5. 4. Relative biological effectiveness in proton therapy: accounting for variability and uncertainties

   Författare :Jakob Ödén; Iuliana Toma-Dasu; Kjell Eriksson; Radhe Mohan; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; proton therapy; relative biological effectiveness; linear energy transfer; proton track-end optimisation; radiation-induced toxicity; Medical Radiation Physics; medicinsk strålningsfysik;

   Sammanfattning : Radiation therapy is widely used for treatments of malignant diseases. The search for the optimal radiation treatment approach for a specific case is a complex task, ultimately seeking to maximise the tumour control probability (TCP) while minimising the normal tissue complication probability (NTCP). LÄS MER

7. 5. Radiation therapy of upper gastrointestinal cancers with scanned proton beams : A treatment planning study

   Författare :Gracinda Mondlane; Albert Siegbahn; Michael Gubanski; Iuliana Toma-Dasu; Crister Ceberg; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Treatment planning; gastric cancer; liver metastases; photon beam therapy; proton beam therapy; dosimetric comparison; normal tissue complication probability; risk of radiation-induced secondary cancer; patient selection; Medical Radiation Physics; medicinsk strålningsfysik;

   Sammanfattning : Proton beam therapy (PBT), using scanned beams, is an emerging modality used for the treatment of cancer. The clinical advantages of PBT, compared to commonly used photon beam therapy, have been demonstrated in different studies. LÄS MER