Sökning: "Photoreceptors"
Visar resultat 11 - 15 av 47 avhandlingar innehållade ordet Photoreceptors.
11. Regulation of Drosophila Jun by phosphorylation and the ubiquitin system during eye development
Sammanfattning : The goal of these studies has been to elucidate the biological relevance of post-translational modifications in the context of a living organism. The model system used is photoreceptor differentiation during development of the compound eye in the fruit fly Drosophila melanogaster. LÄS MER
12. Intracellular mechanisms in rd1 mouse retinal degeneration
Sammanfattning : Retinitis pigmentosa (RP) is an inherited disorder and the leading cause of visual impairment in the working age population. It is caused by a number of different genetic mutations, all of which cause the rod photoreceptors to degenerate. As the rods become few in numbers, the cones will also begin to die, resulting in total blindness. LÄS MER
13. Computational Studies of Photobiological Keto-Enol Reactions and Chromophores
Sammanfattning : This thesis presents computational chemistry studies of keto-enol reactions and chromophores of photobiological signicance.The rst part of the thesis is concerned with two protein-bound chromophores that, depending on the chemical conditions, can exist in a number of dierent ketonic and enolic forms. LÄS MER
14. Isotope labeling of proteins for spectroscopic studies
Sammanfattning : Protein structural dynamics have been closely tied to the molecular mechanisms controlling for example enzyme activities. In my work, I have mainly studied the bacteriophytochrome from Deinococcus radiodurans. LÄS MER
15. Photoreceptor degeneration, second order neuron remodeling and glia reactivity in an in vivo and in vitro model of retinal neurodegeneration
Sammanfattning : Photoreceptors have the ability to last during the entire lifespan of an individual. Being the first line of neurons in the visual transduction pathway, their health and maintenance is eminent for proper retinal function. However, photoreceptors are susceptible to neurodegenerative retinal dystrophies. LÄS MER