Sökning: "Phosphoinositid-30H-kinase-related-kinases PIKK"

Hittade 1 avhandling innehållade orden Phosphoinositid-30H-kinase-related-kinases PIKK.

1. 1. The role of TPPII in apoptosis control and treatment of malignant disease

   Författare :Hong Xu; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :proteasome; tripeptidyl peptidase II; apoptosis; inhibitor of apoptosis LAP ; p53; Phosphoinositid-30H-kinase-related-kinases PIKK ;

   Sammanfattning : Degradation of cytosolic proteins depends largely on the proteasome. This complex contains a catalytic core (20S) and an accessory complex (19S) that recognizes ubiquitinated substrates and translocates these to the catalytic sites in the 20S particle. LÄS MER