Sökning: "Phosphatidic acid"

Visar resultat 1 - 5 av 10 avhandlingar innehållade orden Phosphatidic acid.

1. 1. A molecular chaperone that governs membrane contact sites and lipid metabolism

   Författare :Sergi Tosal Castaño; Sabrina Büttner; W. Mike Henne; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Yeast; nucleus-vacuole junctions; proteostasis; unfolded protein response; fatty acid elongation; molekylär biovetenskap; Molecular Bioscience;

   Sammanfattning : Transmembrane proteins represent almost one third of the total cellular proteome, and the majority of them requires translocation into the endoplasmic reticulum (ER) to be folded, sorted and transported to their final subcellular destination. High translational rates during exponential cell growth result in a massive influx of immature proteins into the ER, requiring rapid and accurate folding. LÄS MER

3. 2. LIPASES AND PHOSPHOLIPASES IN PHOSPHOLIPID SYNTHESIS

   Författare :Carmen Virto; Bioteknik; []
   Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; transphosphatidylation; acylation; vinyl ester; Phospholipid synthesis; lysophospholipid; kinetics; Biotechnology; Bioteknik;

   Sammanfattning : The synthesis of phospholipids with defined fatty acid and polar head composition catalysed by lipases and phospholipases was investigated. Lipases from Rhizopus arrhizus and Candida antarctica were used for the direct acylation of DL-a-glycerophosphate and L-a-glycerophosphatidylcholine, with different fatty acids. LÄS MER

4. 3. Isolation and characterization of lipid-associated and neurosecretory polypeptides

   Författare :Margareta Stark; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Lipid-interacting proteins play important roles in all living organisms. This thesis focuses on isolation and characterization of an enzyme in the triacylglycerol biosynthesis (phosphatidic acid phosphatase, PAP), hydrophobic polypeptides in bile, and polypeptides in cerebrospinal fluid. LÄS MER

5. 4. Phosphatidylinositol phosphate kinases in the moss Physcomitrella patens

   Författare :Laura Saavedra; Biokemi och Strukturbiologi; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES;

   Sammanfattning : Phosphatidylinositol(4,5)bisphosphate, [PtdIns(4,5)P2], is a signalling lipid which is involved in many important processes in animal cells such as cytoskeleton organization, intracellular vesicular trafficking, secretion, cell motility, regulation of ion channels, and nuclear signalling pathways. In contrast to the animal field, much less is known about the roles of PtdIns(4,5)P2 and its synthesizing enzyme, phosphatidylinositol phosphate kinase (PtdInsP kinase), in plants. LÄS MER

7. 5. Defense gene responses toward necrotrophic fungi in Arabidopsis thaliana

   Författare :Hanneke Marjolijn Peele; Sveriges lantbruksuniversitet; Sveriges lantbruksuniversitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES;

   Sammanfattning : Leptosphaeria maculans an ascomycete in the diverse class of Dothideomycetes, is an devastating pathogen on Brassica crops. In this thesis, tools and knowledge in Arabidopsis thaliana was explored to enhance our knowledge on plant defense to this fungus. Mechanisms that to large extent are shared with other necrotrophic fungi. LÄS MER