Sökning: "Pharmacoepidemiology"

Visar resultat 16 - 20 av 25 avhandlingar innehållade ordet Pharmacoepidemiology.

  1. 16. Methods in pharmacoepidemiology : four studies, four settings

    Författare :Anders Sundström; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : In the present thesis, four studies using four different settings and designs are presented in which associations between pharmacological treatments and possible adverse drug reactions are investigated; some methodological considerations identified in them are discussed. In a population-based case-control study, using information from telephone interviews, the association between use of acid-suppressing drugs and the development of acute pancreatitis was investigated. LÄS MER

  3. 17. Pharmacoepidemiology and health economics of adherence to pharmaceutical fracture prevention

    Författare :Oskar Ström; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Background: Osteoporosis is a disease characterized by weak bone, affecting hundreds of millions of people worldwide, predominantly postmenopausal women. The main clinical consequence of the disease is bone fractures and the lifetime risk of any fracture has been estimated at ~55% in Norwegian women. LÄS MER

  4. 18. Methodological challenges in pregnancy pharmacoepidemiology : the case of antiseizure medication and offspring neurodevelopment

    Författare :Viktor H. Ahlqvist; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : This thesis is driven by the overarching aim of elucidating methodological challenges inherent in pharmacoepidemiology during pregnancy, with a particular focus on antiseizure medications. In Study I, a substantial surge in antiseizure medication use in the United Kingdom is observed, notably linked to increases in psychiatric indications. LÄS MER

  5. 19. The toxicological pharmacoepidemiology of suicide : population-based studies on psychotropic-medication use in Sweden

    Författare :Jonas Forsman; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The act of completed suicide is a complex phenomenon associated with numerous identified individual and combined risk factors. Mental illness and related disorders confer among the highest risks of completed suicide and have consequently been targeted through pharmacological interventions. LÄS MER

  7. 20. Pharmacoepidemiology of Antibiotics, Weak Opioids and Statins with Special Reference to Socioeconomic Aspects - an Ecological Approach

    Författare :Karin Henricson; Institutionen för hälsovetenskaper; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Farmakologi; toxicology; pharmacy; pharmacognosy; Pharmacological sciences; statins; weak opioids; antibiotics; effectiveness; socioeconomic factors; Ecologic studies; drug utilisation; farmakognosi; farmaci; toxikologi; Social medicine; Socialmedicin; samhällsmedicin;

    Sammanfattning : The influence of socioeconomic factors on drug utilisation has been studied by pharmacoepidemiological analyses involving 1) drugs that are used to cure disease, such as antibiotics, 2) drugs that are used to alleviate symptoms, such as weak opioids, and 3) drugs that are used to prevent disease, such as statins. In a large Swedish city (Malmö), the utilisation of four major drug groups (ATC-groups A = alimentation, C = circulation, N = nervous system, and R = respiration) correlated positively with an unfavourable socioeconomic situation, most pronouncedly with group N and least so with group R. LÄS MER