Avancerad sökning

Visar resultat 1 - 5 av 25 avhandlingar som matchar ovanstående sökkriterier.

  1. 1. The influence of gender and depression on drug utilization : Pharmacoepidemiological research in Sweden

    Författare :Lena Thunander Sundbom; Göran Frenning; Kerstin Hedborg; Susanna Wallerstedt; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; adherence; anxiety; depression; drug utilization; gender; pharmacoepidemiology; prescription drugs; self-report; Farmakoepidemiologi; Pharmacoepidemiology; Health-Promoting Work;

    Sammanfattning : Background Drug use has increased over recent decades, and is especially great among women and among people with mental health problems. To take advantage of the full potential of drugs and to avoid drug-related problems, drug prescription needs to be correct and the drugs need to be taken according to the prescribed regimens. LÄS MER

  2. 2. Real-Time Monitoring of Healthcare Interventions in Routine Care : Effectiveness and Safety of Newly Introduced Medicines

    Författare :Thomas Cars; Johan Sundström; Björn Wettermark; Martin Neovius; Til Stürmer; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Electronic Health Records; Comparative Effectiveness Research; Comparative Safety Research; Sequential drug monitoring; propensity score; real-world data; infliximab; TNF-inhibitors; dronedarone; amiodarone; flecainide; Farmakoepidemiologi; Pharmacoepidemiology;

    Sammanfattning : Before market authorization of new medicines, their efficacy and safety are evaluated using randomized controlled trials. While there is no doubt about the scientific value of randomized trials, they are usually conducted in selected populations with questionable generalizability to routine care. LÄS MER

  3. 3. Prostate Cancer; Metabolic Risk Factors, Drug Utilisation, Adverse Drug Reactions

    Författare :Birgitta Grundmark; Lars Holmberg; Björn Zethelius; Gunnar Engström; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Prostate cancer; Epidemiology; Pharmacoepidemiology; Metabolic Syndrome; Selenium; Smoking; hOGG1; MnSOD; Competing Risk; Adherence; Persistance; Medical Possession Ratio; MPR; Signal Detection; PRR; proportional reporting ratio; ULSAM; PcBaSE; EudraVigilance; SPDR; Swedish Prescribe Drug Registry; NPCR; National Prostate Cancer Registry; SDR; Signal; disproportionality analysis; PRR-TA; EudraVigilance; Epidemiology; Epidemiologi; Kirurgi; särskilt urologi; Urology; Oncology; Onkologi; Geriatrics; Geriatrik;

    Sammanfattning : Increased possibilities during the last decades for early detection of prostate cancer have sparked research on preventable or treatable risk factors and on improvements in therapy. Treatments of the disease still entail significant side effects potentially affecting men during the rest of their lives. LÄS MER

  4. 4. Inappropriate prescribing, non-adherence to long-term medications and related morbidities : Pharmacoepidemiological aspects

    Författare :Khedidja Hedna; Staffan Hägg; Max Petzold; Katja Hakkarainen; Johan Fastbom; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Drug-related morbidity; medication adherence; inappropriate prescribing; elderly; drug utilisation; pharmacoepidemiology;

    Sammanfattning : Background: Inappropriate use of medications (IUM), in particular inappropriate prescribing and non-adherence to prescribed medications, are important causes of drug-related morbidities (DRMs). They are increasing problems with the ageing populations and the growing burden of chronic conditions. LÄS MER

  5. 5. Drug-related morbidity and mortality : Pharmacoepidemiological aspects

    Författare :Anna K. Jönsson; Staffan Hägg; Johan Ahlner; Henrik Druid; Jörg Mörland; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Adverse drug reactions; pharmacoepidemiology; antipsychotics; venous; thromboembolism; warfarin; haemorrhage; intoxication; medico-legal autopsies; mortality; Läkemedelsbiverkningar; farmakoepidemiologi; antipsykotika; venös tromboembolism; warfarin; blödning; intoxikation; rättsmedicinska obduktioner; fatal; Clinical pharmacology; Klinisk farmakologi;

    Sammanfattning : Adverse drug reactions (ADRs) constitute a significant health problem with consequences for the patient as well as for society. Suspected ADRs have been reported to occur in about 2-14% of hospitalised patients. In about 5% of deceased hospitalised patients suspected ADRs may have caused or contributed to the fatal outcome. LÄS MER