Sökning: "Pharmaceutical chemistry"
Visar resultat 6 - 10 av 244 avhandlingar innehållade orden Pharmaceutical chemistry.
6. Pharmaceutical Nanocomposites : Structure–Mobility–Functionality Relationships in the Amorphous State
Sammanfattning : Amorphous materials are found in pharmaceutical formulations both as excipients and active ingredients. Indeed, these formulations are becoming an essential strategy for incorporating drugs into well-performing solid dosage forms. LÄS MER
7. Application of Artificial Gel Antibodies for the Detection and Quantification of Proteins in Biological Fluids
Sammanfattning : The molecular-imprinting method has previously been used for the synthesis of artificial gel antibodies, highly selective for various proteins. In present study, we have synthesized artificial gel antibodies against haemoglobin, albumin and different forms of growth hormone with the aim to develop a simple and rapid procedure to measure the concentration of these protein biomarkers in samples of clinical interest. LÄS MER
8. Investigating polymorphism in small molecules using three-dimensional electron diffraction
Sammanfattning : For scientific, regulatory and intellectual property reasons, the discovery and characterisation of polymorphic systems is an integral aspect of the development process of any solid-formulated drug product. Yet, these studies are often hindered by crystal quality and size, poor yields and the generation of mixtures of phases. LÄS MER
9. C1 Building Blocks: New Approaches for Thiomethylations and Esterification
Sammanfattning : The thioether motif is found in numerous pharmaceuticals. The simplest form of this motif, the methyl-thioether is similarly found in many biologically active compounds and has exhibited many advantageous properties. The installation of the thiomethyl moiety can be troublesome due to the toxicity and malodor of small sulfur reagents. LÄS MER
10. Tertiary Alcohol- or β-Hydroxy γ-Lactam-Based HIV-1 Protease Inhibitors : Microwave Applications in Batch and Continuous Flow Organic Synthesis
Sammanfattning : Since the outbreak of the HIV/AIDS pandemic in the 1980s, the disease has cost the lives of over 30 million people, and a further 33 million are currently living with the HIV infection. With the appropriate treatment, HIV/AIDS can today be regarded as a chronic but manageable disease. LÄS MER
