Sökning: "Pharmaceutical Sciences"
Visar resultat 1 - 5 av 985 avhandlingar innehållade orden Pharmaceutical Sciences.
1. On the crystallization of membrane proteins in lipidic sponge and cubic phases
Sammanfattning : Membrane proteins are involved in many important biological processes and in order to understand their mechanism, their three-dimensional structures need to be elucidated to high resolution by for example X-ray crystallography. However, there is only limited structural knowledge for membrane proteins which is partly explained by the difficulties in obtaining well-diffracting crystals. LÄS MER
2. Lipid-based liquid crystals as drug delivery vehicles for antimicrobial peptides
Sammanfattning : The development of antimicrobial resistance is a great challenge within the health sector around the world. The demand for new efficient treatments is alarming in order to treat various bacterial infections in the near future. Antimicrobial peptides (AMPs) are a group of novel antibiotics that have gain more and more attraction the past decade. LÄS MER
3. Effect of elevated pCO2 and environmental oxazepam on the behavior and physiology of teleost fish
Sammanfattning : This doctoral thesis investigated the effect of two aquatic pollutants on the behavior and physiology of teleost fish: i) elevated concentrations of carbon dioxide (CO2) in the context of ocean acidification and ii) low concentrations of the anxiolytic pharmaceutical oxazepam in the context of pharmaceutical pollution.Anthropogenic emissions of CO2 are lowering the pH of the oceans. LÄS MER
4. Sperm Membrane Channels, Receptors and Kinematics : Using boar spermatozoa for drug toxicity screening
Sammanfattning : Internal fertilization usually implies that a spermatozoon, with intact attributes for zygote formation, passes all hurdles during its transport through the female genitalia and reaches the oocyte. During this journey, millions to billions of other spermatozoa perish. LÄS MER
5. Toxicometabolomics and biotransformation product screening in single zebrafish embryos
Sammanfattning : Over the last decade environmental agencies worldwide have escalated their work to phase out animal testing for the purposes of chemical regulation. Meanwhile the number of commercially available chemicals and the requirements for hazard assessments have both increased, creating a large need for substitution of traditional in vivo assays with in vitro tests. LÄS MER
