Sökning: "Pharmaceutical R D"
Visar resultat 1 - 5 av 20 avhandlingar innehållade orden Pharmaceutical R D.
1. Development of Palladium-Promoted 11C/12C-Carbonylations and Radiosynthesis of Amyloid PET Ligands
Sammanfattning : In the first part of this thesis, palladium(0)-catalyzed and -mediated carbonylations are discussed. Paper I describes a new method for the safe, efficient use of a solid carbon monoxide source in the synthesis of primary and secondary benzamides. LÄS MER
2. Palladium(0)-Catalyzed Synthesis of Spirocycles and Supercritical Chemistry using a Resistively Heated Flow Reactor
Sammanfattning : This doctoral thesis focusses on an effective and selective approach to the synthesis of spirocycles using palladium(0)-catalyzed Mizoroki-Heck reactions. In addition, selective and efficient chemistry was highlighted by the design and evaluation of a novel resistively heated system for continuous flow (CF) synthesis for high-temperature and high-pressure applications. LÄS MER
3. Integrated Product and Process Design for Mass Customization: A Road Towards Patient Access to Individualized Pharmaceutical Therapy
Sammanfattning : Individualized pharmaceutical therapy strives to attain optimal health outcomes a priori in all patients treated with pharmaceutical products by tailoring these products to each patient’s holistic needs. However, existing mass-produced pharmaceutical products are not available in sufficient variety to enable adequate tailoring to the diverse needs of individuals. LÄS MER
4. Capabilities for frequent innovation : Managing the early project phases in the pharmaceutical R&D process
Sammanfattning : Despite their recognized significance for project success and innovation, the management of the early project phases is still an under-researched area in project management. For organizations to secure a continuous stream of innovation, the utilization of capabilities is crucial for managing the early phases of R&D projects. LÄS MER
5. Change in the Pharmaceutical Industry : Aspects on Innovation, Entrepreneurship, Openness, and Decision Making
Sammanfattning : Over the past century, the pharmaceutical industry has been a major contributor of individual and population health and societal wealth. Its products and services have contributed to longevity of large groups of patients and symptom relief from major diseases. LÄS MER