Sökning: "Peyer’s patches"

Visar resultat 6 - 10 av 14 avhandlingar innehållade orden Peyer’s patches.

  1. 6. Starch Microparticles as an Oral Vaccine Adjuvant with Emphasis on the Differentiation of the Immune Response

    Författare :Linda Stertman; Ingvar Sjöholm; Kjell-Olov Grönvik; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmaceutics; Vaccine adjuvant; Microparticles; Oral immunisation; Th1 Th2 differentiation; Mucosal immune response; Uptake; M cell; Galenisk farmaci; Pharmaceutics; Galenisk farmaci;

    Sammanfattning : Polyacryl starch microparticles have been developed as an oral vaccine adjuvant capable of inducing strong local and systemic immune responses in mice. In this thesis, the starch microparticles were studied in order to increase basic understanding of their function. LÄS MER

  3. 7. The response of mast cells and serglycin-dependent proteases to parasitic infection : studies on mast cells during Toxoplasma gondii (murine) and Dictyocaulus vivparus (bovine) infection

    Författare :Osama Sawesi; Sveriges lantbruksuniversitet; Sveriges lantbruksuniversitet; []
    Nyckelord :LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES;

    Sammanfattning : The proteoglycan (PG), serglycin (SG), is expressed in several hematopoietic cells and studies of the SG knockout mice (SG-/-) revealed prominent effects on the storage of certain mouse mast cell proteases (mMCPs) such as mMCP-4, -5 and -6.In this thesis, the role of SGPG during parasitic infection was addressed. LÄS MER

  4. 8. Recruitment, Differentiation, and Function of monocytes during Salmonella infection

    Författare :Anna Rydström; Göteborgs universitet; []
    Nyckelord :Salmonella; Monocyte; Neutrophil; Chemokine; Toll-like receptor; Differentiation;

    Sammanfattning : Monocytes are a heterogeneous population in the blood with an enormous plasticity whose fate and functions are dictated by the microenvironment. They are phenotypically and functionally related to neutrophils and dendritic cells (DCs) and share an overlapping expression pattern of surface molecules with these cells. LÄS MER

  5. 9. Regulation of Autoimmunity and Inflammation by microRNAs and Environmental Factors

    Författare :Neivis Tormo-Badia; Diabetes - immunovirologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Tolerance is crucial for maintaining immunological balance and avoid autoimmune diseases like type 1 diabetes and the inflammatory bowel disease, ulcerative colitis (UC). In Study I, we have investigated the regulatory role of a class of noncoding RNAs, the miRNAs, during thymocyte development of the where central tolerance is established. LÄS MER

  7. 10. Persistent infection by Yersinia pseudotuberculosis

    Författare :Kemal Avican; Maria Fällman; Wyndham W. Lathem; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Persistent infection; RNA-seq; PMNs; Yersinia; Transcriptome; wrba; fnr; rovA; arcA; rfaH; molekylärbiologi; Molecular Biology; Infectious Diseases; infektionssjukdomar; immunologi; Immunology;

    Sammanfattning : Enteropathogenic Yersinia species can infect many mammalian organs such as the small intestine, cecum, Peyer’s patches, liver, spleen, and lung and cause diseases that resemble a typhoid-like syndrome, as seen for other enteropathogens. We found that sublethal infection doses of Y. LÄS MER