Sökning: "Peyer’s patches"

Visar resultat 1 - 5 av 12 avhandlingar innehållade orden Peyer’s patches.

  1. 1. Mucosal dendritic cells in inflammatory bowel disease

    Detta är en avhandling från Linköping : Linköping University Electronic Press

    Författare :Sa'ad Yislam Salim; Linköpings universitet.; Linköpings universitet.; [2009]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Blood; Crohn s disease; dendritic cells; E. coli; FACS; follicle-associated; epithelium; human; ileum; mixed lymphocyte reaction; permeability; Peyer s patches; SAMP1 YitFc; Ussing chambers; villous epithelium; MEDICINE; MEDICIN;

    Sammanfattning : Crohn's disease, a chronic inflammation of the bowel, is a multi-factorial condition where uncontrolled immune responses to luminal bacteria occur in genetically predisposed individuals. The first observable clinical signs are small ulcers that form at a specialised form of epithelium, follicle-associated epithelium (FAB). LÄS MER

  2. 2. Barrier function of the Follicle-Associated Epithelium in Stress and Crohn's disease

    Detta är en avhandling från Institutionen för biomedicin och kirurgi

    Författare :Åsa Keita; Linköpings universitet.; Linköpings universitet.; [2007]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Corticotropin-releasing hormone; Crohn’s disease; 51Cr- EDTA; Escherichia coli; follicle-associated epithelium; horseradish peroxidase; human; ileum; inflammatory bowel disease; intestinal mucosa; mast cell; M cell; permeability; Peyer’s patches; rat; Ussing chamber; vasoactive intestinal peptide; villus epithelium; MEDICINE Surgery; MEDICIN Kirurgi;

    Sammanfattning : Crohns sjukdom är en kronisk inflammatorisk tarmsjukdom av okänd orsak. Det tidigaste tecknet på Crohns sjukdom är mikroskopiska sår i det s.k. follikelassocierade epitelet (FAE) som täcker ansamlingar av immunceller i tarmen. LÄS MER

  3. 3. Particle Transcytosis Across the Human Intestinal Epithelium Model Development and Target Identification for Improved Drug Delivery

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Elisabet Gullberg; Uppsala universitet.; [2005]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmaceutics; M-cell; FAE; Peyer´s patches; oral vaccination; uptake; endocytosis; Galenisk farmaci; PHARMACY Pharmaceutics; FARMACI Galenisk farmaci;

    Sammanfattning : The use of nano- and micro-particulate carriers as delivery systems for oral vaccines has been under investigation for several decades. Surprisingly little is known of their uptake in the human intestine, despite the fact that substantial improvement is required to achieve adequate immune responses in man after oral administration. LÄS MER

  4. 4. Role of mast cells and probiotics in the regulation of intestinal barrier function

    Detta är en avhandling från Linköping : Linköping University Electronic Press

    Författare :Anders Carlsson; Linköpings universitet.; Linköpings universitet.; [2013]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : The intestinal mucosa is the largest contact area and one of the most important barriers to the outside environment. It is highly specialized in aiding us digest and absorb nutrients. It is daily exposed to several potentially dangerous substances and microorganisms, which if they were allowed to pass into the body, could give rise to diseases. LÄS MER

  5. 5. Starch Microparticles as an Oral Vaccine Adjuvant with Emphasis on the Differentiation of the Immune Response

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Linda Stertman; Uppsala universitet.; [2004]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmaceutics; Vaccine adjuvant; Microparticles; Oral immunisation; Th1 Th2 differentiation; Mucosal immune response; Uptake; M cell; Galenisk farmaci; PHARMACY Pharmaceutics; FARMACI Galenisk farmaci;

    Sammanfattning : Polyacryl starch microparticles have been developed as an oral vaccine adjuvant capable of inducing strong local and systemic immune responses in mice. In this thesis, the starch microparticles were studied in order to increase basic understanding of their function. LÄS MER