Sökning: "Petra Wäster"
Hittade 3 avhandlingar innehållade orden Petra Wäster.
1. UVA/B induced redox alterations and apoptosis in human melanocytes
Sammanfattning : Malignant melanoma is one of the most rapidly increasing cancers and accounts for about three-quarter of all skin cancer deaths worldwide. Despite compelling evidence that ultraviolet (UV) irradiation causes melanoma the knowledge how various wavelength spectra affect the balance between proliferation and apoptosis controlling the homeostasis of the melanocyte population is still limited. LÄS MER
2. Lysosomal Membrane Stability and Cathepsins in Cell Death
Sammanfattning : Lysosomes are acidic organelles that are critically involved in a number of physiological processes, including macromolecule degradation, endocytosis, autophagy, exocytosis and cholesterol homeostasis. Several pathological conditions, such as cancer, neurodegenerative disorders and lysosomal storage diseases, involve lysosomal disturbances, indicating the importance of the organelle for correct cellular function. LÄS MER
3. Dealing with damaged lysosomes : Impact of lysosomal membrane stability in health and disease
Sammanfattning : The lysosome is the main unit for degradation and plays important roles in various cellular processes, such as nutrient sensing, cholesterol regulation and cell death. Consequently, altered lysosomal function contributes to, or even causes, several diseases. LÄS MER