Sökning: "Pertussis"

Visar resultat 1 - 5 av 43 avhandlingar innehållade ordet Pertussis.

  1. 1. Aspects of pertussis, pertussis vaccination and adverse events associated with aluminum adsorbed vaccines

    Författare :Elisabet Bergfors; Göteborgs universitet; []
    Nyckelord :Pertussis; parapertussis; pertussis toxoid; vaccine; vaccination; vaccine trial; adjuvant; aluminium; adsorbed vaccines; adverse event; pruritic nodules; itching nodules; granuloma; sensitisation; hypersensitivity; contact allergy;

    Sammanfattning : The thesis originates in a clinical study of one of the new acellular pertussis vaccines performed in Göteborg in the 1990s. The monocomponent vaccine, pertussis toxoid adsorbed to aluminium hydroxide, had previously been shown to have an efficacy of 71%. LÄS MER

  3. 2. Interactions of human C4BP with Bordetella pertussis and Streptococcus pyogenes

    Författare :Karin Berggård; Lund Dermatologi och venereologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; M protein; antigenic variation; phagocytosis resistance; complement; C4b-binding protein C4BP ; Bordetella pertussis; Streptococcus pyogenes; Microbiology; bacteriology; virology; mycology; Mikrobiologi; bakteriologi; virologi; mykologi;

    Sammanfattning : Many microorganisms have developed mechanisms to protect themselves against attack from the complement system of the host. One possible mechanism for a microorganism to evade complement attack is to bind a human complement regulator, which may allow the microorganism to down-regulate complement activation. LÄS MER

  4. 3. B-cell responses after pertussis vaccination

    Författare :Maja Jahnmatz; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Despite years of vaccination efforts, whooping cough, or pertussis, is not under control. Although immunization has greatly reduced the disease incidence, thousands of children die of whooping cough each year. LÄS MER

  5. 4. Epidemiological characterisation of Bordatella pertussis in Sweden, 1970-2004

    Författare :Abdolreza Advani; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Worldwide, Bordetella pertussis causes some 50 million cases of pertussis, and an estimated 2-300,000 fatalities each year. In Sweden vaccination against pertussis was introduced in the 1950s using diphtheria-tetanus-whole-cell pertussis vaccine (DTPw) until 1979, when it was withdrawn due to concerns about effectiveness. LÄS MER

  7. 5. Molecular detection and epidemiological studies of atypical bacteria causing respiratory tract infections

    Författare :Karolina Gullsby; Kåre Bondeson; Björn Olsen; Puolakkainen Mirja; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Chlamydia pneumoniae; Mycoplasma pneumoniae; Bordetella pertussis; real-time PCR; P1 typing; MLVA; whole-genome sequencing; macrolide resistance; molecular diagnostics; molecular epidemiology;

    Sammanfattning : Respiratory infections are common causes of morbidity and mortality. Chlamydia pneumoniae, Mycoplasma pneumoniae and Bordetella pertussis cause respiratory infection, often with similar symptoms. Molecular diagnostic methods are preferred since these bacteria are difficult to culture. LÄS MER