Sökning: "Pernilla örtqvist"

Hittade 1 avhandling innehållade orden Pernilla örtqvist.

  1. 1. On the Design and Synthesis of Hepatitis C Virus NS3 Protease Inhibitors : From Tripeptides to Achiral Compounds

    Författare :Pernilla Örtqvist; Anja Sandström; Mats Larhed; Anders Hallberg; Morten Grøtli; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; hepatitis C virus; NS3 protease inhibitor; structure-activity relationship; resistance; 2 1H -pyrazinone; phenylglycine; Pharmaceutical chemistry; Farmaceutisk kemi; Medicinal Chemistry; Läkemedelskemi;

    Sammanfattning : Infection by the hepatitis C virus (HCV) leads to inflammation of the liver, i.e. hepatitis. The acute infection often progresses to a chronic phase during which the liver function is gradually impaired. LÄS MER