Sökning: "Permeabilization"

Visar resultat 1 - 5 av 37 avhandlingar innehållade ordet Permeabilization.

1. 1. Lysosomal Membrane Permeabilization : A Cellular Suicide Strategy

   Författare :Ann-Charlotte Johansson; Karin Öllinger; Karin Roberg; Boris Zhivotovsky; Linköpings universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; apoptosis; lysosomes; lysosomal membrane permeabilization; cathepsins; Bax; Bid; mitochondria; caspases; Cell and molecular biology; Cell- och molekylärbiologi;

   Sammanfattning : In the last decade, a tremendous gain in knowledge concerning the molecular events of apoptosis signaling and execution has been achieved.The aim of this thesis was to clarify the role of lysosomal membrane permeabilization and lysosomal proteases, cathepsins, in signaling for apoptosis. LÄS MER

3. 2. Antibody-based subcellular localization of the human proteome

   Författare :Marie Skogs; Emma Lundberg; Hans Blom; Cecilia Williams; KTH; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Human proteome; Subcellular localization; Organelles; Immunofluorescence; Fixation; Permeabilization; Antibody validation; Bioteknologi; Biotechnology;

   Sammanfattning : This thesis describes the use of antibodies and immunofluorescence for subcellular localization of proteins. The key objective is the creation of an open-source atlas with information on the subcellular location of every human protein. LÄS MER

4. 3. Induction of Mast Cell Apoptosis via Granule Permeabilization : A Novel Approach to Target Mast Cells

   Författare :Aida Paivandy; Gunnar Pejler; Magda Babina; Uppsala universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Mast cells; Granules; Apoptosis; Reactive oxygen species; ROS; Lysosomotropic agents; Mefloquine; Immunologi; Immunology; Biokemi; Biochemistry;

   Sammanfattning : Mast cells are densely granulated tissue-resident immune cells that play an important role in orchestrating inflammatory responses. Dysregulated increases in the numbers and activation status of mast cells can have deleterious consequences for the body in various inflammatory diseases. LÄS MER

5. 4. Inactivation, Cell Injury and Growth of Microorganisms Exposed to Pulsed Electric Fields Using a Continuous Process

   Författare :Kristina Aronsson; Chalmers tekniska högskola; []
   Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Leuconostoc mesenteroides; PEF; Listeria innocua; cell injury; flow-through treatment chamber; membrane permeabilization; post-processing growth; microbial inactivation; pulsed electric fields; Escherichia coli; Saccharomyces cerevisiae;

   Sammanfattning : Pulsed electric fields (PEF) is a proven technology to inactivate microorganisms under non-thermal conditions. The PEF technology has a potential as a "quality friendly" alternative to traditional methods of food preservation. LÄS MER

7. 5. Pulsed Electric Field Treatment of Plant Tissue

   Författare :Mustafa Fincan; Livsmedelsteknik; []
   Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; bimodal Fickian diffusion model; Food and drink technology; Livsmedelsteknik; generalized Maxwell model; onion Neutral Red; visualization; red beetroot; potato; epidermis; plant tissue; electroporation; Cell permeabilization; Pulsed electric field; PEF;

   Sammanfattning : A pulsed electric field (PEF) is a newly emerged non-thermal food processing technology which has characteristic effects on the cell membrane. PEF processing involves subjecting food to short, repeated pulses of a high electric field between an anode and a cathode. LÄS MER