Sökning: "Peripheral aberrations"
Visar resultat 16 - 20 av 32 avhandlingar innehållade orden Peripheral aberrations.
16. bHLH transcription factors in differentiating neuroblastoma cells
Sammanfattning : Neuroblastoma is a tumor of the sympathetic nervous system, and arises during early childhood. The tumor is highly heterogeneous and evidence, such as expression of genes normally only expressed during embryonic and fetal stages, suggests that the tumor is of embryonic origin and that the tumor arises as a consequence of perturbed differentiation during the development of the sympathetic nervous system. LÄS MER
17. Cellular effects after exposure to mixed beams of ionizing radiation
Sammanfattning : Mixed beams of ionizing radiation in our environment originate from space, the bedrock and our own houses. Radiotherapy patients treated with boron neutron capture therapy or with high energy photons are also exposed to mixed beams of gamma radiation and neutrons. LÄS MER
18. Regulation of neurotrophic signaling molecules in motor neurons, primary sensory neurons and target tissues in senescence
Sammanfattning : A hallmark of senescence is sensorimotor impairment, characterized by gait disturbance, deficits in postural control, and muscle weakness. The object of this thesis work was to elucidate some of the molecular basis underlying these disturbances, mainly referring to the occurrence of characteristic changes in gene-expression pattern, especially, alterations in trophic signaling associated with the phenotypic changes seen in motoneurons as well as primary sensory neurons and target muscles during aging. LÄS MER
19. Leukocyte transmigration and gene expression in healthy subjects and patients with renal failure-application of the skin chamber technique
Sammanfattning : The migration of leukocytes from the peripheral circulation into infected or injured tissue is a fundamental step in the host-defense mechanism. The skin chamber technique is a well documented method for studies of leukocyte trans migration and function in vivo. LÄS MER
20. Exposure, telomere length, and cancer risk
Sammanfattning : Telomeres are tandem repeats of TTAGGG at the end of eukaryotic chromosomes. Telomeres play a key role in chromosome stability and regulation of the cellular lifespan. Telomeres are shortened during cell division, and probably, by not yet well characterised factors in the environment. LÄS MER