Sökning: "Peripheral aberrations"

Visar resultat 11 - 15 av 32 avhandlingar innehållade orden Peripheral aberrations.

  1. 11. Schizophrenia as a systemic disorder : studies of peripheral and central biological functions

    Författare :Lena Flyckt; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :schizophrenia; systemic disease; membrane function; tyrosine transport; muscle biopsy; muscle fibre atrophy; macro EMG; cognitive functions; neurological signs; finger-tapping;

    Sammanfattning : Psychiatric disturbances with an onset in adulthood may show subtle signs in childhood and school age. This is particularly applicable to patients with schizophrenia. LÄS MER

  3. 12. Acute lung injury : incidence and predictors of outcome with special reference to inhaled nitric oxide

    Författare :Owe Luhr; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Respiratory distress syndrome; Adult; -drug-therapy; -mortality; Treatment; -outcome; Nitric oxide; therapeutic-use; administration-and-dosage; -adverse effects; Mutagenicity; tests; Chromosome aberrations; Risk factors; Logistic models; Prospective studies.;

    Sammanfattning : This work started out as a critical examination of the initial clinical experiences with inhalation of nitric oxide (INO) to patients with acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) in Scandinavia 1991-1994. During this examination, we found that epidemiological data and prognostic factors were lacking in Scandinavia for these patient groups, making it difficult to evaluate new therapies. LÄS MER

  4. 13. Regulation of immunity in Multiple Sclerosis : CD4+ T cells and the influence of natalizumab

    Författare :Måns Edström; Jan Ernerudh; Maria Jenmalm; Charlotte Dahle; Finn Sellebjerg; Örebro universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Multiple sclerosis (MS) is an autoimmune disease targeting the central nervous system (CNS) and the most common neurological cause of disability in young adults. In most cases, the disease course is characterised by the cycling of relapses and remissions, so called relapsing-remitting MS (RR-MS). LÄS MER

  5. 14. Array based genetic profiling of bone and soft tissue tumors

    Författare :Karolin Hansén Nord; Avdelningen för klinisk genetik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : In this thesis, genetic alterations in bone and soft tissue tumors have been investigated with the purpose of identifying regions of importance for tumor development, diagnosis and prognosis. This has primarily been performed by array comparative genomic hybridization analysis and gene expression profiling of cytogenetically analyzed tumors. LÄS MER

  7. 15. Cytogenetic studies of normal kidney tissue and renal cell carcinoma

    Författare :Peter Elfving; Malmö (Abrahamsson) Urologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cytology; Klinisk genetik; Clinical genetics; nonneoplastic kidney tissue; renal cell carcinoma; trisomy 7; Cytogenetics; FISH; oncology; cancerology; Cytologi; onkologi; cancer;

    Sammanfattning : In the present thesis normal kidney tissue and renal cell carcinoma (RCC) were studied by cytogenetic and fluorescence in situ hybridization (FISH) methods to investigate chromosomal aberrations. In the first study, 4 samples of nonneoplastic kidney tissue were cultured for cytogenetic analysis and trisomy 7 was found in all cases in 3-15% of the cells. LÄS MER