Sökning: "Periodontitis neutrophils"

Visar resultat 1 - 5 av 6 avhandlingar innehållade orden Periodontitis neutrophils.

  1. 1. Hyperreactive peripheral neutrophils in periodontitis : FCc receptor activation and plasma proteins

    Författare :Margareta Fredriksson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Periodontitis neutrophils; oxygen radicals; smoking; priming.;

    Sammanfattning : It is now well established that adult and juvenile periodontitis are associated with a hyperreactivity of the peripheral neutrophils when measured as increased generation of free oxygen radicals after stimulation of the Fcgamma-receptors. Aim: The aims of these investigations were to study if the increased radical generation was: 1) located intra- or extracellularly and attributed to a specific oxygen species or various activation pathways, 2) connected with "priming" (pre-stimulation only disclosed by a secondary activation), 3) associated with systemic aberrations in plasma parameters induced by the periodontal disease or cigarette smoking or 4) related to the neutrophil production of the cytokines IL-8 and TNFalpha after stimulation. LÄS MER

  3. 2. Monocyte and Neutrophil Inflammatory Responses to the Periodontopathogen Porphyromonas gingivalis

    Författare :Kartheyaene Jayaprakash; Torbjörn Bengtsson; Allan Sirsjö; Hazem Khalaf; Anders Johansson; Örebro universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Monocytes; Neutrophils; Porphyromonas gingivalis; Gingipains; Biomedicin; Biomedicine;

    Sammanfattning : Periodontitis is one of the most common adult infections. Duing bacteremia in healthy individuals or patients with chronic periodontitis, a number of oral bacteria such as Porphyromonas gingivalis encounter inflammatory cells in the blood eg. platelets, neutrophils and monocytes. LÄS MER

  4. 3. Neutrophil recruitment in periodontal disease

    Författare :Agnes Dahlstrand Rudin; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; neutrophil; periodontitis; P. gingivalis; F. nucleatum; SCFA; FFAR2; CD177; A1AT;

    Sammanfattning : Neutrophils are the first immune cells to arrive in infected or injured tissues, where they engulf microbes and clean up cell debris. Periodontitis is one of the typical symptoms of both neutropenia and defect neutrophil functionality, suggesting an important role for these cells in maintenance of periodontal health. LÄS MER

  5. 4. Plasminogen in periodontitis and wound repair

    Författare :Rima Sulniute; Tor Ny; Daniel A Lawrence; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : The plasminogen activator (PA) system plays a critical role in many physiological and pathological processes, such as fibrinolysis, extracellular matrix (ECM) degradation, wound healing, inflammation, and cancer. The key component of the PA system is plasmin, a broad-spectrum serine protease that is derived from its inactive form, plasminogen. LÄS MER

  7. 5. Gene Polymorphisms and Related Cell Markers in Periodontitis Lesions

    Författare :Mauro Donati; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Allele; B-lymphocyte; cell-surface molecule; cytokine; gene expression; genotype; gingivitis; host response; inflammation; periodontal disease;

    Sammanfattning : Inflammatory and immune reactions to microbial plaque are the predominant features of periodontitis. Epidemiological studies revealed that differences in periodontitis among individuals could not be explained by differences in oral hygiene alone and that not everybody is equally susceptible. LÄS MER