Sökning: "Per Bergström"
Visar resultat 6 - 10 av 33 avhandlingar innehållade orden Per Bergström.
6. Apolipoprotein A-IV and Transthyretin in Swedish Forms of Systemic Amyloidosis
Sammanfattning : Over 20 different plasma proteins have been shown to have the capacity to undergo conformational changes and self-assemble into highly stable and insoluble amyloid fibrils. One, transthyretin (TTR), consists of 127 amino acid residues arranged in eight β-strands (named A to H) and is involved in two different clinical forms of amyloidosis. LÄS MER
7. Contextualising a South African social innovation for maternal and child health to mothers with experiences of migration in Sweden
Sammanfattning : Despite a universally accessible and high-quality welfare system, disparities in health and wellbeing persist between families who have migrated to Sweden and the native population. The South African Mentor Mother programme, a social innovation for maternal and child health among socially disadvantaged communities, was transferred and adapted to benefit mothers and pregnant women with experiences of migrating to Sweden. LÄS MER
8. Computational and Experimental Models for the Prediction of Intestinal Drug Solubility and Absorption
Sammanfattning : New effective experimental techniques in medicinal chemistry and pharmacology have resulted in a vast increase in the number of pharmacologically interesting compounds. However, the number of new drugs undergoing clinical trial has not augmented at the same pace, which in part has been attributed to poor absorption of the compounds. LÄS MER
9. In vitro and in silico prediction of drug-drug interactions with transport proteins
Sammanfattning : Drug transport across cells and cell membranes in the human body is crucial for the pharmacological effect of drugs. Active transport governed by transport proteins plays an important role in this process. A vast number of transport proteins with a wide tissue distribution have been identified during the last 15 years. LÄS MER
10. Microgels as drug delivery vehicles : loading and release of amphiphilic drugs
Sammanfattning : Polyelectrolyte microgels are used as delivery vehicles for amphiphilic drugs in, e.g., treatments of liver cancer by a method called trans-arterial chemoembolization. LÄS MER
