Sökning: "Per Agvald"

Hittade 1 avhandling innehållade orden Per Agvald.

  1. 1. Nitric oxide generation from nitroglycerin and other no-donors measured in the lung and studies on nitrate tolerance in the cardiovascular system

    Författare :Per Agvald; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Exhaled; nitric oxide; nitroglycerin; nitrite; temperature; tolerance; hypoxia;

    Sammanfattning : Nitroglycerin (GTN) and compounds referred to as nitrovasodilators or NOdonors are frequently used in the treatment of ischemic heart disease. The common mode of action for these drugs is liberation of nitric oxide (NO). Nitric oxide evokes relaxation of smooth muscle through activation of guanylate cyclase with subsequent formation of eGMP. LÄS MER