Sökning: "Peptides"

Visar resultat 21 - 25 av 1142 avhandlingar innehållade ordet Peptides.

  1. 21. Interfacing HPLC with MALDI- and ESI-MS for Automated High Sensitivity Analysis of Proteins and Peptides

    Författare :Tasso Miliotis; Lund Institutionen för kliniska vetenskaper; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; automated; phosphorylation; ZAP-70; peptides; proteins; comprehensive; multidimensional; two-dimensional; piezoelectric; microdispenser; flow-through; ESI-MS MS; Capillary HPLC; MALDI-TOF MS; Analytical chemistry; Analytisk kemi;

    Sammanfattning : The research described in this thesis has an interdisciplinary approach dealing with chemical, biological, and technical issues. One objective was to interface miniaturized liquid chromatography (LC) to mass spectrometry, i.e. MALDI-TOF MS and ESI-MS, in an unattended mode for high sensitivity determination of proteins and peptides. LÄS MER

  3. 22. Development of methods for the solid-phase synthesis of backbone modified peptides and small organic molecules

    Författare :Kalle Kaljuste; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Neurochemistry; Peptides; cyclic;

    Sammanfattning : .... LÄS MER

  4. 23. Cellular Dyes and Bioactive Peptides - Cell Membrane Interactions and Cellular Uptake

    Författare :Maria Matson Dzebo; Chalmers tekniska högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Membrane Interactions; Spectroscopy; Cell-Penetrating Peptides; Bioactive Peptides; Cell Membrane; Confocal Laser Scanning Microscopy; Cellular Uptake; AF-16; Voltage-Sensitive Dyes; Cell Dyes; Antisecretory Factor; Ruthenium Complexes; Isothermal Titration Calorimetry; Flow-Cytometry;

    Sammanfattning : Knowledge about mechanisms behind interactions of molecules with biomembranes and cellular uptake is very important for understanding biological processes and for drug design. The work described in this thesis has focused on interactions of cellular dyes and bioactive peptides with cells and the cell membrane. LÄS MER

  5. 24. Novel Endogenous Antimicrobial Peptides

    Författare :Emma Nordahl; Lund Dermatologi och venereologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; D5; HK; C3a; HMWK; complement; heparin-binding; antibacterial; Antimicrbial peptide; AMP;

    Sammanfattning : Antimicrobial peptides serve as a first line of defence against invading microorganisms and are an essential part of our fast innate immune system. They are ancient molecules found in all classes of life. Antimicrobial peptides rapidly kill a broad spectrum of microbes and are immunomodulatory, i.e. LÄS MER

  7. 25. Biophysical studies of membrane interacting peptides derived from viral and Prion proteins

    Författare :Kamila Oglęcka; Astrid Gräslund; Stephen White; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Prion peptides; Doppel peptide; Influenza fusion peptides; peptide-membrane interactions; translocation; linear dichroism; circular dichroism; Biophysics; Biofysik; Biophysics; biofysik;

    Sammanfattning : This thesis focuses on peptides derived from the Prion, Doppel and Influenza haemagglutinin proteins in the context of bilayer interactions with model membranes and live cells. The studies involve spectroscopic techniques like fluorescence, fluorescence correlation spectroscopy (FCS), circular and linear dichroism (CD and LD), confocal fluorescence microscopy and NMR. LÄS MER