Sökning: "Peptide immunology"
Visar resultat 1 - 5 av 64 avhandlingar innehållade orden Peptide immunology.
1. Vaccine development strategies applied to the Plasmodium falciparum malaria antigen 332
Sammanfattning : Malaria is one of the major infectious diseases in the world with regard to mortality and morbidity, and the development of a vaccine against the malaria parasite Plasmodium falciparum is considered of high priority. The aim of the work presented in this thesis was to develop and characterize recombinant vaccine constructs based on the P. LÄS MER
2. Immunological and functional properties of a non-repeat region in Plasmodium falciparum antigen Pf155/RESA
Sammanfattning : Plasmodium falciparum malaria is one of the most prevalent of all the great insect-borne diseases causing high morbidity and mortality in humans. As conventional anti-malarial treatment is becoming increasingly inefficient, alternative approaches to combat the parasite, like vaccine development, are of high priority. LÄS MER
3. B cell deviations and type 1 diabetes in the NOD mouse
Sammanfattning : Type 1 diabetes (T1D) is a chronic autoimmune disease in which the insulin producing β-cells in the pancreatic islets of Langerhans are selectively attacked by the immune system. The β-cells are destroyed resulting in a reduced or eliminated insulin production, which in turn lead to a high blood glucose level. LÄS MER
4. Identification of candidate genes involved in Mercury Toxicokinetics and Mercury Induced Autoimmunity
Sammanfattning : BACKGROUND: Autoimmune diseases require the involvement and activation of immune cells and occur when the body builds up an immune response against its own tissues. This process takes place due to the inability to distinguish self-antigen from foreign antigen. Systemic autoimmunity represents an important cause of morbidity and mortality in humans. LÄS MER
5. T-cell regulation of immune responses to the Plasmodium falciparum antigen Pf155/RESA
Sammanfattning : Plasmodium falciparum is the cause of the most severe malaria inhumans. Due to the rapid resurgence of malaria in many parts of theworld extensive efforts have been made during the last few years todefine several P.falciparum antigens for inclusion in a vaccine. LÄS MER