Sökning: "Pegah Rouhi"

Hittade 1 avhandling innehållade orden Pegah Rouhi.

1. 1. Role of angiogenesis in cancer invasion and metastasis

   Författare :Pegah Rouhi; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Cancer metastasis is a complex process that involves an elaborate interplay between malignant cells and various host cellular and molecular components. The metastatic cascade consists of several discrete but non-separable steps, including: 1) malignant transformation of cells; 2) intravasation and dissemination of tumor cells into the circulation or lymphatic system; 3) transport of malignant cells to distal organs and tissues; 4) adherence of tumor cells to distal sites; 5) formation of the initial metastatic niches, and 6) angiogenesis-dependent re-growth of metastatic foci to clinically detectable tumors. LÄS MER