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Visar resultat 1 - 5 av 7 avhandlingar som matchar ovanstående sökkriterier.
1. Fibroblast Growth Factor Receptor-1 Function in Vasculo- and Angiogenesis
Sammanfattning : During development of the mammalian embryo, spatial and temporal expression of fibroblast growth factors (FGFs) and their cognate receptors are vital in the regulation of a number of patterning processes. Inappropriate or decreased expression leads to severe malformations and even embryonic death. LÄS MER
2. Pancreatic Islet Transplantation : Modifications of Islet Properties to Improve Graft Survival
Sammanfattning : During the past decade clinical islet transplantation has become a viable strategy for curing type 1 diabetes. The limited supply of organs, together with the requirement for islets from multiple donors to achieve insulin independence, has greatly limited the application of this approach. LÄS MER
3. Strategies in Cochlear Nerve Regeneration, Guidance and Protection : Prospects for Future Cochlear Implants
Sammanfattning : Today, it is possible to restore hearing in congenitally deaf children and severely hearing-impaired adults through cochlear implants (CIs). A CI consists of an external sound processor that provides acoustically induced signals to an internal receiver. LÄS MER
4. Inflammation and immunothrombosis in cerebral cavernous malformation : Novel molecular targets for the treatment of an incurable disease
Sammanfattning : Cerebral cavernous malformation (CCM) is a vascular disease that causes mulberry-like lesions (cavernomas) in the central nervous system (CNS). Cavernomas are fragile, leaky and prone to rupture which may cause symptoms such as epileptic seizures, focal neurological deficits and hemorrhagic strokes. CCM lesions can appear sporadically in 0. LÄS MER
5. Neutrophil extracellular traps as potential therapeutic targets to prevent tumor-induced organ failure and metastasis
Sammanfattning : Cancer does not only affect surrounding tissues, but also leads to complications at distant sites. The reason for this is that tumors secrete factors and prime cells that travel through the body, making cancer a systemic disease. In fact, cancer death is mostly caused by systemic complications such as metastasis, organ failure or thrombosis. LÄS MER