Sökning: "Pedro-Otavio Campos-Lima de"

Hittade 1 avhandling innehållade orden Pedro-Otavio Campos-Lima de.

1. 1. Control of Epstein-Barr virus infection by cytotoxic T lymphocytes

   Författare :Pedro-Otavio de Campos-Lima; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Epstein-Barr virus; Cytotoxic T lymphocytes; T cell receptor; CTLescape mutants;

   Sammanfattning : Cytotoxic T lymphocytes (CTL) play a critical role in response to Epstein-Barr virus (EBV), a widespread human herpes virus that persists in healthy carriers as a latent infection of B cells and is implicated in the pathogenesis of lymphoid and epithelial cell malignancies. Six virus encoded nuclear antigens, EBNA1-6, and three membrane proteins, LMP1, -2A and -2B, are regularly detected in EBV transformed lymphoblastoid cell lines (LCLs). LÄS MER